eF-site ID 6d0f-A
PDB Code 6d0f
Chain A

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Title Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide
Classification NUCLEAR PROTEIN
Compound Estrogen receptor
Source (6D0F)
Sequence A:  LTADQMVSALLDAEPPILYSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEH
PGKLLFAPNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGE
EFVCLKSIILLNSGVYTLEEKDHIHRVLDKITDTLIHLMA
KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSD
LLLEMLDAH
Description


Functional site

1) chain A
residue 346
type
sequence L
description binding site for residue FYS A 601
source : AC1

2) chain A
residue 347
type
sequence T
description binding site for residue FYS A 601
source : AC1

3) chain A
residue 353
type
sequence E
description binding site for residue FYS A 601
source : AC1

4) chain A
residue 387
type
sequence L
description binding site for residue FYS A 601
source : AC1

5) chain A
residue 391
type
sequence L
description binding site for residue FYS A 601
source : AC1

6) chain A
residue 394
type
sequence R
description binding site for residue FYS A 601
source : AC1

7) chain A
residue 404
type
sequence F
description binding site for residue FYS A 601
source : AC1

8) chain A
residue 428
type
sequence L
description binding site for residue FYS A 601
source : AC1

9) chain A
residue 521
type
sequence G
description binding site for residue FYS A 601
source : AC1

10) chain A
residue 524
type
sequence H
description binding site for residue FYS A 601
source : AC1

11) chain A
residue 525
type
sequence L
description binding site for residue FYS A 601
source : AC1

12) chain A
residue 540
type
sequence L
description binding site for residue FYS A 601
source : AC1

13) chain A
residue 537
type MOD_RES
sequence S
description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106
source Swiss-Prot : SWS_FT_FI1

14) chain A
residue 447
type LIPID
sequence C
description S-palmitoyl cysteine => ECO:0000250
source Swiss-Prot : SWS_FT_FI2


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