eF-site ID 6czn-B PDB Code 6czn Chain B click to enlarge Title Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide Classification NUCLEAR PROTEIN Compound Estrogen receptor Source (6CZN) Sequence B:  LALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLA DRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIG LVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLA TSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHIHRVLDK ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKG MEHLYSMKPLSDLLLEMLDAHR Description Functional site 1) chain B residue 346 type sequence L description binding site for residue FNJ B 601 source : AC2 2) chain B residue 347 type sequence T description binding site for residue FNJ B 601 source : AC2 3) chain B residue 350 type sequence A description binding site for residue FNJ B 601 source : AC2 4) chain B residue 353 type sequence E description binding site for residue FNJ B 601 source : AC2 5) chain B residue 387 type sequence L description binding site for residue FNJ B 601 source : AC2 6) chain B residue 394 type sequence R description binding site for residue FNJ B 601 source : AC2 7) chain B residue 404 type sequence F description binding site for residue FNJ B 601 source : AC2 8) chain B residue 421 type sequence M description binding site for residue FNJ B 601 source : AC2 9) chain B residue 428 type sequence L description binding site for residue FNJ B 601 source : AC2 10) chain B residue 521 type sequence G description binding site for residue FNJ B 601 source : AC2 11) chain B residue 524 type sequence H description binding site for residue FNJ B 601 source : AC2 12) chain B residue 525 type sequence L description binding site for residue FNJ B 601 source : AC2 13) chain B residue 340 type MOD_RES sequence A description Phosphoserine; by CK2 => ECO:0000269|PubMed:7838153 source Swiss-Prot : SWS_FT_FI3 14) chain B residue 433 type MOD_RES sequence S description Asymmetric dimethylarginine; by PRMT1 => ECO:0000269|PubMed:18657504, ECO:0000269|PubMed:24498420 source Swiss-Prot : SWS_FT_FI4 15) chain B residue 358-423 type DNA_BIND sequence INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSME HPGKLLFAPNLLLDRNQGKCVEGMVE description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 358-378 type ZN_FING sequence INWAKRVPGFVDLTLHDQVHL description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 17) chain B residue 394-418 type ZN_FING sequence RSMEHPGKLLFAPNLLLDRNQGKCV description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2

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