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eF-site ID
|
6ct7-L |
|
PDB Code
|
6ct7 |
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Chain
|
L |
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click to enlarge
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Title
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Fab of anti-a-synuclein antibody BIIB054 in complex with acetylated a-synuclein peptide (1-10) |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
BIIB054 Fab light chain |
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Source
|
(6CT7) |
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Sequence
|
L: |
SYELTQPPSVSVSPGQTARITCSGEALPMQFAHWYQQRPG
KAPVIVVYKDSERPSGVPERFSGSSSGTTATLTITGVQAE
DEADYYCQSPDSTNTYEVFGGGTKLTVLSQPKAAPSVTLF
PPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG
VETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHE
GSTVEKTVAPTE
|
|
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Description
|
(1) |
BIIB054 Fab light chain, BIIB054 Fab heavy chain, ACE-MET-ASP-VAL-PHE-MET-LYS-GLY-LEU-SER-LYS
|
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Functional site
|
|
|
1)
|
chain |
L |
| residue |
36 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue IPA L 301
|
| source |
: AC1
|
|
|
2)
|
chain |
L |
| residue |
46 |
| type |
|
| sequence |
V
|
| description |
binding site for residue IPA L 301
|
| source |
: AC1
|
|
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3)
|
chain |
L |
| residue |
84 |
| type |
|
| sequence |
D
|
| description |
binding site for residue IPA L 302
|
| source |
: AC2
|
|
|
4)
|
chain |
L |
| residue |
101 |
| type |
|
| sequence |
G
|
| description |
binding site for residue IPA L 302
|
| source |
: AC2
|
|
|
5)
|
chain |
L |
| residue |
193-199 |
| type |
prosite |
| sequence |
YSCQVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
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