|
|
eF-site ID
|
6ct7-A |
|
PDB Code
|
6ct7 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Fab of anti-a-synuclein antibody BIIB054 in complex with acetylated a-synuclein peptide (1-10) |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
BIIB054 Fab light chain |
|
Source
|
(6CT7) |
|
|
Sequence
|
A: |
EVQLVESGGGLVEPGGSLRLSCAVSGFDFEKAWMSWVRQA
PGQGLQWVARIKSTADGGTTSYAAPVEGRFIISRDDSRNM
LYLQMNSLKTEDTAVYYCTSAHWGQGTLVTVSSASTKGPS
VFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTF
PAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTK
VDKRVEPK
|
|
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Description
|
(1) |
BIIB054 Fab light chain, BIIB054 Fab heavy chain, ACE-MET-ASP-VAL-PHE-MET-LYS-GLY-LEU-SER-LYS
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
105 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue IPA H 301
|
| source |
: AC3
|
|
|
2)
|
chain |
A |
| residue |
27 |
| type |
|
| sequence |
F
|
| description |
binding site for Di-peptide ACE T 0 and MET T 1
|
| source |
: AC5
|
|
|
3)
|
chain |
A |
| residue |
102 |
| type |
|
| sequence |
H
|
| description |
binding site for Di-peptide ACE T 0 and MET T 1
|
| source |
: AC5
|
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|
|