eF-site ID 6csc-AB PDB Code 6csc Chain A, B click to enlarge Title CHICKEN CITRATE SYNTHASE COMPLEX WITH TRIFLUOROACETONYL-COA AND CITRATE Classification OXO-ACID-LYASE Compound CITRATE SYNTHASE Source ORGANISM_COMMON: chicken; ORGANISM_SCIENTIFIC: Gallus gallus; Sequence A:  ASSTNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDM SYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPK AGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAAL PSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAE GINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSI GAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEG GNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQE VLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGH AVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNV LLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVS RALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG B:  TNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYG GMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPKAGG GEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALPSH VVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIN RTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSIGAI DSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNV SAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLL WLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGHAVL RKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNVLLE QGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRAL GVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG Description Functional site 1) chain A residue 274 type sequence H description ENZYME ACTIVE SITE. source : ACA 2) chain A residue 320 type sequence H description ENZYME ACTIVE SITE. source : ACA 3) chain A residue 375 type sequence D description ENZYME ACTIVE SITE. source : ACA 4) chain B residue 274 type sequence H description ENZYME ACTIVE SITE. source : ACB 5) chain B residue 320 type sequence H description ENZYME ACTIVE SITE. source : ACB 6) chain B residue 375 type sequence D description ENZYME ACTIVE SITE. source : ACB 7) chain A residue 46 type sequence R description BINDING SITE FOR RESIDUE COF A 700 source : AC1 8) chain A residue 272 type sequence P description BINDING SITE FOR RESIDUE COF A 700 source : AC1 9) chain A residue 273 type sequence L description BINDING SITE FOR RESIDUE COF A 700 source : AC1 10) chain A residue 274 type sequence H description BINDING SITE FOR RESIDUE COF A 700 source : AC1 11) chain A residue 277 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 12) chain A residue 280 type sequence E description BINDING SITE FOR RESIDUE COF A 700 source : AC1 13) chain A residue 284 type sequence W description BINDING SITE FOR RESIDUE COF A 700 source : AC1 14) chain A residue 313 type sequence R description BINDING SITE FOR RESIDUE COF A 700 source : AC1 15) chain A residue 314 type sequence V description BINDING SITE FOR RESIDUE COF A 700 source : AC1 16) chain A residue 315 type sequence V description BINDING SITE FOR RESIDUE COF A 700 source : AC1 17) chain A residue 316 type sequence P description BINDING SITE FOR RESIDUE COF A 700 source : AC1 18) chain A residue 317 type sequence G description BINDING SITE FOR RESIDUE COF A 700 source : AC1 19) chain A residue 318 type sequence Y description BINDING SITE FOR RESIDUE COF A 700 source : AC1 20) chain A residue 319 type sequence G description BINDING SITE FOR RESIDUE COF A 700 source : AC1 21) chain A residue 320 type sequence H description BINDING SITE FOR RESIDUE COF A 700 source : AC1 22) chain A residue 321 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 23) chain A residue 366 type sequence K description BINDING SITE FOR RESIDUE COF A 700 source : AC1 24) chain A residue 367 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 25) chain A residue 368 type sequence K description BINDING SITE FOR RESIDUE COF A 700 source : AC1 26) chain A residue 373 type sequence N description BINDING SITE FOR RESIDUE COF A 700 source : AC1 27) chain A residue 375 type sequence D description BINDING SITE FOR RESIDUE COF A 700 source : AC1 28) chain B residue 158 type sequence Y description BINDING SITE FOR RESIDUE COF A 700 source : AC1 29) chain B residue 164 type sequence R description BINDING SITE FOR RESIDUE COF A 700 source : AC1 30) chain B residue 419 type sequence L description BINDING SITE FOR RESIDUE COF A 700 source : AC1 31) chain A residue 238 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 32) chain A residue 242 type sequence N description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 33) chain A residue 274 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 34) chain A residue 320 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 35) chain A residue 329 type sequence R description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 36) chain A residue 375 type sequence D description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 37) chain A residue 401 type sequence R description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 38) chain B residue 421 type sequence R description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 39) chain A residue 158 type sequence Y description BINDING SITE FOR RESIDUE COF B 700 source : AC3 40) chain A residue 164 type sequence R description BINDING SITE FOR RESIDUE COF B 700 source : AC3 41) chain A residue 419 type sequence L description BINDING SITE FOR RESIDUE COF B 700 source : AC3 42) chain B residue 46 type sequence R description BINDING SITE FOR RESIDUE COF B 700 source : AC3 43) chain B residue 272 type sequence P description BINDING SITE FOR RESIDUE COF B 700 source : AC3 44) chain B residue 273 type sequence L description BINDING SITE FOR RESIDUE COF B 700 source : AC3 45) chain B residue 274 type sequence H description BINDING SITE FOR RESIDUE COF B 700 source : AC3 46) chain B residue 277 type sequence A description BINDING SITE FOR RESIDUE COF B 700 source : AC3 47) chain B residue 313 type sequence R description BINDING SITE FOR RESIDUE COF B 700 source : AC3 48) chain B residue 314 type sequence V description BINDING SITE FOR RESIDUE COF B 700 source : AC3 49) chain B residue 315 type sequence V description BINDING SITE FOR RESIDUE COF B 700 source : AC3 50) chain B residue 316 type sequence P description BINDING SITE FOR RESIDUE COF B 700 source : AC3 51) chain B residue 317 type sequence G description BINDING SITE FOR RESIDUE COF B 700 source : AC3 52) chain B residue 318 type sequence Y description BINDING SITE FOR RESIDUE COF B 700 source : AC3 53) chain B residue 319 type sequence G description BINDING SITE FOR RESIDUE COF B 700 source : AC3 54) chain B residue 320 type sequence H description BINDING SITE FOR RESIDUE COF B 700 source : AC3 55) chain B residue 321 type sequence A description BINDING SITE FOR RESIDUE COF B 700 source : AC3 56) chain B residue 366 type sequence K description BINDING SITE FOR RESIDUE COF B 700 source : AC3 57) chain B residue 367 type sequence A description BINDING SITE FOR RESIDUE COF B 700 source : AC3 58) chain B residue 368 type sequence K description BINDING SITE FOR RESIDUE COF B 700 source : AC3 59) chain B residue 373 type sequence N description BINDING SITE FOR RESIDUE COF B 700 source : AC3 60) chain B residue 375 type sequence D description BINDING SITE FOR RESIDUE COF B 700 source : AC3 61) chain A residue 421 type sequence R description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 62) chain B residue 238 type sequence H description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 63) chain B residue 242 type sequence N description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 64) chain B residue 274 type sequence H description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 65) chain B residue 320 type sequence H description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 66) chain B residue 329 type sequence R description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 67) chain B residue 375 type sequence D description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 68) chain B residue 401 type sequence R description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 69) chain A residue 244 type catalytic sequence S description 78 source MCSA : MCSA1 70) chain A residue 274 type catalytic sequence H description 78 source MCSA : MCSA1 71) chain A residue 320 type catalytic sequence H description 78 source MCSA : MCSA1 72) chain A residue 329 type catalytic sequence R description 78 source MCSA : MCSA1 73) chain A residue 375 type catalytic sequence D description 78 source MCSA : MCSA1 74) chain B residue 244 type catalytic sequence S description 78 source MCSA : MCSA2 75) chain B residue 274 type catalytic sequence H description 78 source MCSA : MCSA2 76) chain B residue 320 type catalytic sequence H description 78 source MCSA : MCSA2 77) chain B residue 329 type catalytic sequence R description 78 source MCSA : MCSA2 78) chain B residue 375 type catalytic sequence D description 78 source MCSA : MCSA2 79) chain A residue 317-329 type prosite sequence GYGHAVLRKTDPR description CITRATE_SYNTHASE Citrate synthase signature. GYGHaVl.RktDPR source prosite : PS00480 80) chain A residue 274 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 81) chain A residue 320 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 82) chain A residue 375 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 83) chain B residue 274 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 84) chain B residue 320 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 85) chain B residue 375 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1

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