eF-site ID 6csc-A PDB Code 6csc Chain A click to enlarge Title CHICKEN CITRATE SYNTHASE COMPLEX WITH TRIFLUOROACETONYL-COA AND CITRATE Classification OXO-ACID-LYASE Compound CITRATE SYNTHASE Source ORGANISM_COMMON: chicken; ORGANISM_SCIENTIFIC: Gallus gallus; Sequence A:  ASSTNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDM SYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPK AGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAAL PSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAE GINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSI GAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEG GNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQE VLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGH AVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNV LLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVS RALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG Description Functional site 1) chain A residue 274 type sequence H description ENZYME ACTIVE SITE. source : ACA 2) chain A residue 320 type sequence H description ENZYME ACTIVE SITE. source : ACA 3) chain A residue 375 type sequence D description ENZYME ACTIVE SITE. source : ACA 4) chain A residue 46 type sequence R description BINDING SITE FOR RESIDUE COF A 700 source : AC1 5) chain A residue 272 type sequence P description BINDING SITE FOR RESIDUE COF A 700 source : AC1 6) chain A residue 273 type sequence L description BINDING SITE FOR RESIDUE COF A 700 source : AC1 7) chain A residue 274 type sequence H description BINDING SITE FOR RESIDUE COF A 700 source : AC1 8) chain A residue 277 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 9) chain A residue 280 type sequence E description BINDING SITE FOR RESIDUE COF A 700 source : AC1 10) chain A residue 284 type sequence W description BINDING SITE FOR RESIDUE COF A 700 source : AC1 11) chain A residue 313 type sequence R description BINDING SITE FOR RESIDUE COF A 700 source : AC1 12) chain A residue 314 type sequence V description BINDING SITE FOR RESIDUE COF A 700 source : AC1 13) chain A residue 315 type sequence V description BINDING SITE FOR RESIDUE COF A 700 source : AC1 14) chain A residue 316 type sequence P description BINDING SITE FOR RESIDUE COF A 700 source : AC1 15) chain A residue 317 type sequence G description BINDING SITE FOR RESIDUE COF A 700 source : AC1 16) chain A residue 318 type sequence Y description BINDING SITE FOR RESIDUE COF A 700 source : AC1 17) chain A residue 319 type sequence G description BINDING SITE FOR RESIDUE COF A 700 source : AC1 18) chain A residue 320 type sequence H description BINDING SITE FOR RESIDUE COF A 700 source : AC1 19) chain A residue 321 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 20) chain A residue 366 type sequence K description BINDING SITE FOR RESIDUE COF A 700 source : AC1 21) chain A residue 367 type sequence A description BINDING SITE FOR RESIDUE COF A 700 source : AC1 22) chain A residue 368 type sequence K description BINDING SITE FOR RESIDUE COF A 700 source : AC1 23) chain A residue 373 type sequence N description BINDING SITE FOR RESIDUE COF A 700 source : AC1 24) chain A residue 375 type sequence D description BINDING SITE FOR RESIDUE COF A 700 source : AC1 25) chain A residue 238 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 26) chain A residue 242 type sequence N description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 27) chain A residue 274 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 28) chain A residue 320 type sequence H description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 29) chain A residue 329 type sequence R description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 30) chain A residue 375 type sequence D description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 31) chain A residue 401 type sequence R description BINDING SITE FOR RESIDUE CIT A 701 source : AC2 32) chain A residue 158 type sequence Y description BINDING SITE FOR RESIDUE COF B 700 source : AC3 33) chain A residue 164 type sequence R description BINDING SITE FOR RESIDUE COF B 700 source : AC3 34) chain A residue 419 type sequence L description BINDING SITE FOR RESIDUE COF B 700 source : AC3 35) chain A residue 421 type sequence R description BINDING SITE FOR RESIDUE CIT B 701 source : AC4 36) chain A residue 244 type catalytic sequence S description 78 source MCSA : MCSA1 37) chain A residue 274 type catalytic sequence H description 78 source MCSA : MCSA1 38) chain A residue 320 type catalytic sequence H description 78 source MCSA : MCSA1 39) chain A residue 329 type catalytic sequence R description 78 source MCSA : MCSA1 40) chain A residue 375 type catalytic sequence D description 78 source MCSA : MCSA1 41) chain A residue 274 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 42) chain A residue 320 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI1 43) chain A residue 375 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 44) chain A residue 317-329 type prosite sequence GYGHAVLRKTDPR description CITRATE_SYNTHASE Citrate synthase signature. GYGHaVl.RktDPR source prosite : PS00480

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