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eF-site ID
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6cmo-R |
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PDB Code
|
6cmo |
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Chain
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R |
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click to enlarge
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Title
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Rhodopsin-Gi complex |
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Classification
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SIGNALING PROTEIN |
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Compound
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chimera protein of Soluble cytochrome b562 and Rhodopsin |
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Source
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(6CMO) |
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Sequence
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R: |
MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSML
AAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLA
VADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG
GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT
WVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNN
ESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES
ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQG
SCFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTT
ICC
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Description
|
(1) |
Soluble cytochrome b562,Rhodopsin, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Fab light chain, Fab Heavy chain
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Functional site
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1)
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chain |
R |
| residue |
4 |
| type |
|
| ligand |
|
| sequence |
T
|
| description |
binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
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| source |
: AC1
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2)
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chain |
R |
| residue |
15 |
| type |
|
| ligand |
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| sequence |
N
|
| description |
binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
|
| source |
: AC1
|
|
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3)
|
chain |
R |
| residue |
18 |
| type |
|
| ligand |
|
| sequence |
G
|
| description |
binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
|
| source |
: AC1
|
|
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4)
|
chain |
R |
| residue |
20 |
| type |
|
| ligand |
|
| sequence |
V
|
| description |
binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
|
| source |
: AC1
|
|
|
5)
|
chain |
R |
| residue |
21 |
| type |
|
| ligand |
|
| sequence |
R
|
| description |
binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
|
| source |
: AC1
|
|
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6)
|
chain |
R |
| residue |
123-139 |
| type |
prosite |
| ligand |
|
| sequence |
IALWSLVVLAIERYVVV
|
| description |
G-protein coupled receptors family 1 signature.[GSTALIVMFYWC]-[GSTANCPDE]-{EDPKRH}-x-{PQ}-[LIVMNQGA]-{RK}-{RK}-[LIVMFT]-[GSTANC]-[LIVMFYWSTAC]-[DENH]-R-[FYWCSH]-{PE}-x-[LIVM].
|
| source |
prosite : PS00237
|
|
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7)
|
chain |
R |
| residue |
290-306 |
| type |
prosite |
| ligand |
|
| sequence |
IPAFFAKSAAIYNPVIY
|
| description |
Visual pigments (opsins) retinal binding site.[LIVMFWAC]-[PSGAC]-x-{G}-x-[SAC]-K-[STALIMR]-[GSACPNV]-[STACP]-x(2)-[DENF]-[AP]-x(2)-[IY].
|
| source |
prosite : PS00238
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