eF-site ID 6cmo-ABGHLR
PDB Code 6cmo
Chain A, B, G, H, L, R

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Title Rhodopsin-Gi complex
Classification SIGNALING PROTEIN
Compound chimera protein of Soluble cytochrome b562 and Rhodopsin
Source (6CMO)
Sequence A:  MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLG
AGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFD
VGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKK
SPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
B:  QSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPV
GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV
SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSK
SGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
G:  NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAH
AKEDPLLTPVPASENPFR
H:  VQLVESGGGLVQPGGSLRLSCAASGFNFYYSSIHWVRQAP
GKGLEWVASIYSYSGSTSYADSVKGRFTISADTSKNTAYL
QMNSLRAEDTAVYYCARYPWYWWMEKPYLSLYGMDYWGQG
TLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEPKSC
L:  MTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKA
PKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDF
ATYYCQQSSSSLITFGQGTKVEIKRTVAAPSVFIFPPSDS
QLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESV
TEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSS
PVTKSFNRGEC
R:  MCGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSML
AAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLA
VADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLQGFFATLG
GEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFT
WVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNN
ESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQES
ATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQG
SCFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTT
ICC
Description (1)  Soluble cytochrome b562,Rhodopsin, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Fab light chain, Fab Heavy chain


Functional site

1) chain R
residue 4
type
ligand
sequence T
description binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
source : AC1

2) chain R
residue 15
type
ligand
sequence N
description binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
source : AC1

3) chain R
residue 18
type
ligand
sequence G
description binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
source : AC1

4) chain R
residue 20
type
ligand
sequence V
description binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
source : AC1

5) chain R
residue 21
type
ligand
sequence R
description binding site for Poly-Saccharide residues NAG R 501 through NAG R 502 bound to ASN R 15
source : AC1

6) chain R
residue 4
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence T
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_501

7) chain R
residue 9
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence F
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_501

8) chain R
residue 15
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence N
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_501

9) chain R
residue 18
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence G
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_501

10) chain R
residue 20-22
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence VRS
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_501

11) chain R
residue 18
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence G
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_502

12) chain R
residue 21
type binding
ligand NAG: N-ACETYL-D-GLUCOSAMINE
sequence R
description N-ACETYL-D-GLUCOSAMINE binding site
source pdb_hetatom : NAG_6cmo_R_502


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