eF-site ID 6cdo-B PDB Code 6cdo Chain B click to enlarge Title Structure of vaccine-elicited HIV-1 neutralizing antibody vFP16.02 in complex with HIV-1 fusion peptide residue 512-519 Classification IMMUNE SYSTEM Compound vFP16.02 Fab heavy chain Source (6CDO) Sequence B:  DVLMTQTPLSLPVSLGGQASISCRSSQSVVYSDGDTYLEW YLQKPGQSPKLLIYKVSRRFSGVPDRFSGSGSGTDFTLKI SRVETEDLGVYYCFQGSHVPYTFGGGTKLEIKRTVAAPSV FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE VTHQGLSSPVTKSFNRGEC Description (1)  vFP1.01 chimeric mouse antibody heavy chain, vFP1.01 chimeric mouse antibody light chain, HIV-1 fusion peptide residue 512-519 Functional site 1) chain B residue 212 type sequence K description binding site for residue SO4 A 303 source : AC3 2) chain B residue 8 type sequence P description binding site for residue SO4 B 301 source : AC7 3) chain B residue 9 type sequence L description binding site for residue SO4 B 301 source : AC7 4) chain B residue 10 type sequence S description binding site for residue SO4 B 301 source : AC7 5) chain B residue 35 type sequence D description binding site for residue SO4 B 302 source : AC8 6) chain B residue 57 type sequence S description binding site for residue SO4 B 302 source : AC8 7) chain B residue 58 type sequence R description binding site for residue SO4 B 302 source : AC8 8) chain B residue 57 type sequence S description binding site for residue SO4 B 303 source : AC9 9) chain B residue 58 type sequence R description binding site for residue SO4 B 303 source : AC9 10) chain B residue 59 type sequence R description binding site for residue SO4 B 303 source : AC9 11) chain B residue 31 type sequence Y description binding site for residue SO4 B 304 source : AD1 12) chain B residue 97 type sequence S description binding site for residue SO4 B 304 source : AD1 13) chain B residue 98 type sequence H description binding site for residue SO4 B 304 source : AD1 14) chain B residue 195 type sequence K description binding site for residue SO4 B 304 source : AD1 15) chain B residue 197-203 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

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