eF-site ID 6cdo-A PDB Code 6cdo Chain A click to enlarge Title Structure of vaccine-elicited HIV-1 neutralizing antibody vFP16.02 in complex with HIV-1 fusion peptide residue 512-519 Classification IMMUNE SYSTEM Compound vFP16.02 Fab heavy chain Source (6CDO) Sequence A:  QVQLLQSGAELVRPGASVTLSCKASGYAFSDYEIHWVKQT PVRGLDWIGAFDPKSGASASNQKVKGRAILTADKSSSTAY MELRSLTSEDSAVYYCTRLRYFGYFDVWGTGTTVTVSSAS TKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWN SGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI CNVNHKPSNTKVDKKVEPKSCDKGLEVLFQ Description (1)  vFP1.01 chimeric mouse antibody heavy chain, vFP1.01 chimeric mouse antibody light chain, HIV-1 fusion peptide residue 512-519 Functional site 1) chain A residue 40 type sequence T description binding site for residue SO4 A 301 source : AC1 2) chain A residue 41 type sequence P description binding site for residue SO4 A 301 source : AC1 3) chain A residue 42 type sequence V description binding site for residue SO4 A 301 source : AC1 4) chain A residue 43 type sequence R description binding site for residue SO4 A 301 source : AC1 5) chain A residue 8 type sequence G description binding site for residue SO4 A 302 source : AC2 6) chain A residue 206 type sequence K description binding site for residue SO4 A 302 source : AC2 7) chain A residue 133 type sequence S description binding site for residue SO4 A 303 source : AC3 8) chain A residue 134 type sequence K description binding site for residue SO4 A 303 source : AC3 9) chain A residue 223 type sequence K description binding site for residue SO4 A 303 source : AC3 10) chain A residue 14 type sequence P description binding site for residue SO4 A 304 source : AC4 11) chain A residue 117 type sequence S description binding site for residue SO4 A 304 source : AC4 12) chain A residue 118 type sequence S description binding site for residue SO4 A 304 source : AC4 13) chain A residue 25 type sequence S description binding site for residue SO4 A 305 source : AC5 14) chain A residue 26 type sequence G description binding site for residue SO4 A 305 source : AC5 15) chain A residue 13 type sequence R description binding site for residue SO4 A 306 source : AC6 16) chain A residue 74 type sequence K description binding site for residue SO4 A 306 source : AC6 17) chain A residue 120 type sequence S description binding site for residue SO4 A 306 source : AC6 18) chain A residue 199-205 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

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