eF-site ID 6cbi-H
PDB Code 6cbi
Chain H

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Title PCNA in complex with inhibitor
Classification CELL CYCLE
Compound Proliferating cell nuclear antigen
Source (6CBI)
Sequence H:  RRQXSMTEFYH
Description (1)  Proliferating cell nuclear antigen, GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS


Functional site

1) chain H
residue 143
type
sequence R
description binding site for Di-peptide GLN H 144 and DAB H 145
source : AC3

2) chain H
residue 146
type
sequence S
description binding site for Di-peptide GLN H 144 and DAB H 145
source : AC3

3) chain H
residue 149
type
sequence E
description binding site for Di-peptide GLN H 144 and DAB H 145
source : AC3

4) chain H
residue 150
type
sequence F
description binding site for Di-peptide GLN H 144 and DAB H 145
source : AC3

5) chain H
residue 144
type
sequence Q
description binding site for Di-peptide DAB H 145 and SER H 146
source : AC4

6) chain H
residue 147
type
sequence M
description binding site for Di-peptide DAB H 145 and SER H 146
source : AC4

7) chain H
residue 148
type
sequence T
description binding site for Di-peptide DAB H 145 and SER H 146
source : AC4

8) chain H
residue 149
type
sequence E
description binding site for Di-peptide DAB H 145 and SER H 146
source : AC4

9) chain H
residue 150
type
sequence F
description binding site for Di-peptide DAB H 145 and SER H 146
source : AC4

10) chain H
residue 144
type
sequence Q
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

11) chain H
residue 146
type
sequence S
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

12) chain H
residue 147
type
sequence M
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

13) chain H
residue 148
type
sequence T
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

14) chain H
residue 150
type
sequence F
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

15) chain H
residue 152
type
sequence H
description binding site for Di-peptide DAB H 145 and GLU H 149
source : AC5

16) chain H
residue 145
type MOD_RES
sequence X
description Phosphothreonine; by PKA, PKB/AKT1, PIM1 and PIM2 => ECO:0000269|PubMed:10753973, ECO:0000269|PubMed:11463845, ECO:0000269|PubMed:12431783, ECO:0000269|PubMed:16982699, ECO:0000269|PubMed:20307683
source Swiss-Prot : SWS_FT_FI1

17) chain H
residue 146
type MOD_RES
sequence S
description Phosphoserine; by PKC and NUAK1 => ECO:0000269|PubMed:10753973, ECO:0000269|PubMed:25329316
source Swiss-Prot : SWS_FT_FI2


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