eF-site ID 6cbi-A PDB Code 6cbi Chain A click to enlarge Title PCNA in complex with inhibitor Classification CELL CYCLE Compound Proliferating cell nuclear antigen Source (6CBI) Sequence A:  MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSM DSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK CAGNEDIITLRAEDNADTLALVFEAQEKVSDYEMKLMDLD QLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAK DGVKFSASGELGNGNIKLSQTSEEEAVTIEMNEPVQLTFA LRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLK YYLAPKIE Description (1)  Proliferating cell nuclear antigen, GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS Functional site 1) chain A residue 45 type sequence V description binding site for Di-peptide GLN I 144 and DAB I 145 source : AC6 2) chain A residue 252 type sequence A description binding site for Di-peptide GLN I 144 and DAB I 145 source : AC6 3) chain A residue 253 type sequence P description binding site for Di-peptide GLN I 144 and DAB I 145 source : AC6 4) chain A residue 254 type sequence K description binding site for Di-peptide GLN I 144 and DAB I 145 source : AC6 5) chain A residue 256 type sequence E description binding site for Di-peptide GLN I 144 and DAB I 145 source : AC6 6) chain A residue 44 type sequence H description binding site for Di-peptide DAB I 145 and SER I 146 source : AC7 7) chain A residue 252 type sequence A description binding site for Di-peptide DAB I 145 and SER I 146 source : AC7 8) chain A residue 253 type sequence P description binding site for Di-peptide DAB I 145 and SER I 146 source : AC7 9) chain A residue 252 type sequence A description binding site for Di-peptide DAB I 145 and GLU I 149 source : AC8 10) chain A residue 253 type sequence P description binding site for Di-peptide DAB I 145 and GLU I 149 source : AC8 11) chain A residue 254 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI6 12) chain A residue 61-79 type prosite sequence RCDRNLAMGVNLTSMSKIL description PCNA_2 Proliferating cell nuclear antigen signature 2. RCDRnlaMgvnLtSMsKIL source prosite : PS00293 13) chain A residue 34-57 type prosite sequence GVNLQSMDSSHVSLVQLTLRSEGF description PCNA_1 Proliferating cell nuclear antigen signature 1. GVnLqSMDsSHVsLVqLtLrsegF source prosite : PS01251 14) chain A residue 77 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI3 15) chain A residue 80 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 248 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI3 17) chain A residue 211 type MOD_RES sequence Y description Phosphotyrosine; by EGFR => ECO:0000269|PubMed:17115032 source Swiss-Prot : SWS_FT_FI4 18) chain A residue 164 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289 source Swiss-Prot : SWS_FT_FI5

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