eF-site ID 6c2m-D PDB Code 6c2m Chain D click to enlarge Title Crystal structure of HCV NS3/4A protease variant Y56H in complex with MK-5172 Classification HYDROLASE/HYDROLASE Inhibitor Compound NS3 protease Source (C1KIK8_9HEPC) Sequence D:  KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQ VEGEVQIVSTATQTFLATSINGVLWTVHHGAGTRTIASPK GPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVT RHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAG HAVGIFRAAVSTRGVAKAVDFIPVESLETTM Description Functional site 1) chain D residue 1097 type sequence C description binding site for residue ZN D 1201 source : AC8 2) chain D residue 1099 type sequence C description binding site for residue ZN D 1201 source : AC8 3) chain D residue 1145 type sequence C description binding site for residue ZN D 1201 source : AC8 4) chain D residue 1149 type sequence H description binding site for residue ZN D 1201 source : AC8 5) chain D residue 1056 type sequence H description binding site for residue SUE D 1202 source : AC9 6) chain D residue 1057 type sequence H description binding site for residue SUE D 1202 source : AC9 7) chain D residue 1058 type sequence G description binding site for residue SUE D 1202 source : AC9 8) chain D residue 1078 type sequence V description binding site for residue SUE D 1202 source : AC9 9) chain D residue 1081 type sequence D description binding site for residue SUE D 1202 source : AC9 10) chain D residue 1123 type sequence R description binding site for residue SUE D 1202 source : AC9 11) chain D residue 1132 type sequence I description binding site for residue SUE D 1202 source : AC9 12) chain D residue 1135 type sequence L description binding site for residue SUE D 1202 source : AC9 13) chain D residue 1136 type sequence K description binding site for residue SUE D 1202 source : AC9 14) chain D residue 1137 type sequence G description binding site for residue SUE D 1202 source : AC9 15) chain D residue 1138 type sequence S description binding site for residue SUE D 1202 source : AC9 16) chain D residue 1139 type sequence S description binding site for residue SUE D 1202 source : AC9 17) chain D residue 1154 type sequence F description binding site for residue SUE D 1202 source : AC9 18) chain D residue 1155 type sequence R description binding site for residue SUE D 1202 source : AC9 19) chain D residue 1156 type sequence A description binding site for residue SUE D 1202 source : AC9 20) chain D residue 1157 type sequence A description binding site for residue SUE D 1202 source : AC9

Display surface Download Links