eF-site ID 6c07-A PDB Code 6c07 Chain A click to enlarge Title Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum Classification TRANSFERASE Compound S-adenosylmethionine synthase Source (Q5CYE4_CRYPI) Sequence A:  EQFLFSSESVCSGHPDKLCDQISDAILDACLEQDPESFVA CETCTKTGFIMVFGEITTKANVNYERVVRETVKEIGYDSE EKGLDYKTMDVIIKLEQQDKNVEDIGAGDQGMMFGYATNE TKELMPLTHVLATSITRELDYIRVKGVSSRVGWLRPDGKA QVTVEYNCKHGVLIPKRIHTILVSVQHDENIENEEIREFV LENVIKKVCPSDLMDKETRILINPSGRFTIGGPAADAGLT GRKIIVDTYGGWGAHGGGAFSGKDATKVDRSGAYMARLVA KSIVFSGLCSRCLVQVSYGIGIARPLSLYINTFGTAKDGY NDAKLLEIVNKVFDFRPGILIKQLNLKSPIFKKTSSGGHF GRSEEEFLWEKPIILQ Description Functional site 1) chain A residue 288 type sequence G description binding site for residue CL A 501 source : AC1 2) chain A residue 289 type sequence A description binding site for residue CL A 501 source : AC1 3) chain A residue 293 type sequence K description binding site for residue CL A 501 source : AC1 4) chain A residue 266 type sequence D description binding site for residue MG A 502 source : AC2 5) chain A residue 267 type sequence A description binding site for residue MG A 502 source : AC2 6) chain A residue 139 type sequence D description binding site for residue MG A 503 source : AC3 7) chain A residue 254-263 type prosite sequence PSGRFTIGGP description AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGrFTIGGP source prosite : PS00178 8) chain A residue 136-146 type prosite sequence GAGDQGMMFGY description ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGmmfGY source prosite : PS00376 9) chain A residue 286-294 type prosite sequence GGGAFSGKD description ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD source prosite : PS00377

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