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eF-site ID
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6c06-F |
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PDB Code
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6c06 |
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Chain
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F |
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click to enlarge
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Title
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Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin |
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Classification
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transcription/antibiotic |
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Compound
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DNA-directed RNA polymerase subunit alpha |
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Source
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Mycobacterium tuberculosis (A0A045IP01_MYCTX) |
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Sequence
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F: |
FVWDEDESEALRQARKDAELTASADSVRAYLKQIGKVALL
NAEEEVELAKRIEAGLYATQLMTELSERGEKLPAAQRRDM
MWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLI
QEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMAD
QARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAK
EMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDFIED
SEAVVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGL
TDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQ
VLRDYL
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Description
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Functional site
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1)
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chain |
F |
| residue |
319-332 |
| type |
prosite |
| sequence |
DLIQEGNLGLIRAV
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| description |
SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAV
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| source |
prosite : PS00715
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2)
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chain |
F |
| residue |
488-514 |
| type |
prosite |
| sequence |
TLDEIGQVYGVTRERIRQIESKTMSKL
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| description |
SIGMA70_2 Sigma-70 factors family signature 2. TldEIGqvygVTrerIrQIEsktMskL
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| source |
prosite : PS00716
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3)
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chain |
F |
| residue |
295-302 |
| type |
prosite |
| sequence |
LLEANLRL
|
| description |
CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL
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| source |
prosite : PS00867
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4)
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chain |
F |
| residue |
489-508 |
| type |
DNA_BIND |
| sequence |
LDEIGQVYGVTRERIRQIES
|
| description |
H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00963
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| source |
Swiss-Prot : SWS_FT_FI1
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