eF-site ID 6c06-C PDB Code 6c06 Chain C click to enlarge Title Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin Classification transcription/antibiotic Compound DNA-directed RNA polymerase subunit alpha Source Mycobacterium tuberculosis (A0A045IP01_MYCTX) Sequence C:  NSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPR WRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSD PRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKS QTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDE TIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRK RRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVG TDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLA RVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLH EGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQI RVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKE FFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAG LEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPF GFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPID ADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSV ATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTG MELRAAIDAGDVVVAEESGVIEEVSADYITVMHDNGTRRT YRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTD DGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTS IHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGI VRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKA REVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELV RVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLAD GTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAA KGVPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGLL SCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMY IMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFG EMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKG ENIPEPGIPESFKVLLKELQSLCLNVEVLSS Description Functional site 1) chain C residue 1051 type sequence M description binding site for residue FI8 D 1404 source : AC4 2) chain C residue 1052 type sequence I description binding site for residue FI8 D 1404 source : AC4 3) chain C residue 1053 type sequence T description binding site for residue FI8 D 1404 source : AC4 4) chain C residue 1054 type sequence Q description binding site for residue FI8 D 1404 source : AC4 5) chain C residue 1094 type sequence D description binding site for residue FI8 D 1404 source : AC4 6) chain C residue 1096 type sequence T description binding site for residue FI8 D 1404 source : AC4 7) chain C residue 1119 type sequence E description binding site for residue FI8 D 1404 source : AC4 8) chain C residue 1120 type sequence S description binding site for residue FI8 D 1404 source : AC4 9) chain C residue 882-894 type prosite sequence GDKLAGRHGNKGV description RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV source prosite : PS01166

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