eF-site ID 6buq-A PDB Code 6buq Chain A click to enlarge Title Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with barbituric acid Classification HYDROLASE Compound Cyanuric acid amidohydrolase Source (CAH_MOOTA) Sequence A:  MQKVEVFRIPTASPDDISGLATLIDSGKINPAEIVAILGK TEGNGCVNDFTRGFATQSLAMYLAEKLGISREEVVKKVAF IMSGGTEGVMTPHITVFVRKDVAAPAAPGKRLAVGVAFTR DFLPEELGRMEQVNEVARAVKEAMKDAQIDDPRDVHFVQI KCPLLTAERIEDAKRRGKDVVVNDTYKSMAYSRGASALGV ALALGEISADKISNEAICHDWNLYSSVASTSAGVELLNDE IIVVGNSTNSASDLVIGHSVMKDAIDADAVRAALKDAGIR SDDEMDRIVNVLAKAEAASSGTVRGRRNTMLDDSDINHTR SARAVVNAVIASVVGDPMVYVSGGAEHQGPDGGGPIAVIA RV Description Functional site 1) chain A residue 45 type sequence G description binding site for residue MLI A 401 source : AC1 2) chain A residue 52 type sequence R description binding site for residue MLI A 401 source : AC1 3) chain A residue 83 type sequence S description binding site for residue MLI A 401 source : AC1 4) chain A residue 84 type sequence G description binding site for residue MLI A 401 source : AC1 5) chain A residue 161 type sequence K description binding site for residue MLI A 401 source : AC1 6) chain A residue 231 type sequence S description binding site for residue MLI A 401 source : AC1 7) chain A residue 232 type sequence A description binding site for residue MLI A 401 source : AC1 8) chain A residue 328 type sequence R description binding site for residue MLI A 401 source : AC1 9) chain A residue 347 type sequence S description binding site for residue MLI A 401 source : AC1 10) chain A residue 348 type sequence G description binding site for residue MLI A 401 source : AC1 11) chain A residue 301 type sequence E description binding site for residue CA A 402 source : AC2 12) chain A residue 350 type sequence A description binding site for residue CA A 402 source : AC2 13) chain A residue 353 type sequence Q description binding site for residue CA A 402 source : AC2 14) chain A residue 354 type sequence G description binding site for residue CA A 402 source : AC2 15) chain A residue 355 type sequence P description binding site for residue CA A 402 source : AC2 16) chain A residue 358 type sequence G description binding site for residue CA A 402 source : AC2 17) chain A residue 54 type sequence F description binding site for residue NA A 403 source : AC3 18) chain A residue 57 type sequence Q description binding site for residue NA A 403 source : AC3 19) chain A residue 53 type sequence G description binding site for residue PDO A 404 source : AC4 20) chain A residue 56 type sequence T description binding site for residue PDO A 404 source : AC4 21) chain A residue 57 type sequence Q description binding site for residue PDO A 404 source : AC4 22) chain A residue 47 type sequence V description binding site for residue PDO A 405 source : AC5 23) chain A residue 184 type sequence D description binding site for residue PDO A 405 source : AC5 24) chain A residue 185 type sequence T description binding site for residue PDO A 405 source : AC5 25) chain A residue 186 type sequence Y description binding site for residue PDO A 405 source : AC5 26) chain A residue 49 type sequence D description binding site for residue CL A 406 source : AC6 27) chain A residue 50 type sequence F description binding site for residue CL A 406 source : AC6 28) chain A residue 52 type sequence R description binding site for residue CL A 406 source : AC6 29) chain A residue 53 type sequence G description binding site for residue CL A 406 source : AC6 30) chain A residue 234 type sequence V description binding site for residue CL A 406 source : AC6 31) chain A residue 235 type sequence E description binding site for residue CL A 406 source : AC6 32) chain A residue 340 type sequence G description binding site for residue CL B 405 source : AD2 33) chain A residue 87 type sequence E description binding site for residue PDO C 405 source : AD7 34) chain A residue 88 type sequence G description binding site for residue PDO C 405 source : AD7 35) chain A residue 161 type ACT_SITE sequence K description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI1 36) chain A residue 231 type ACT_SITE sequence S description Nucleophile => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI2 37) chain A residue 359 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 38) chain A residue 360 type BINDING sequence P description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 39) chain A residue 363 type BINDING sequence V description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 40) chain A residue 306 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 41) chain A residue 333 type BINDING sequence A description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 42) chain A residue 352 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 43) chain A residue 355 type BINDING sequence P description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 44) chain A residue 358 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 45) chain A residue 193 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 46) chain A residue 52 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 47) chain A residue 83 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 48) chain A residue 231 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI3 49) chain A residue 329 type SITE sequence A description Important for substrate specificity => ECO:0000255|HAMAP-Rule:MF_01989 source Swiss-Prot : SWS_FT_FI4

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