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eF-site ID
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6bqf-B |
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PDB Code
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6bqf |
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Chain
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B |
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click to enlarge
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Title
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Pol II elongation complex with 'dT-AP' at i+1, i-1 position |
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Classification
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TRANSFERASE/TRANSCRIPTION |
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Compound
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DNA-directed RNA polymerase II subunit RPB1 |
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Source
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(6BQF) |
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Sequence
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B: |
DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL
QDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEA
RLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATE
SDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVF
KKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATL
PYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEM
LKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKE
FLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRD
HFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAIN
AKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYS
STLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGL
VKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSP
DATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSM
IRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRK
GHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIA
MQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAA
SIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMA
NILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGY
NQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITET
FEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIG
KTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKF
VKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTA
EGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGD
ASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMA
QIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRS
RDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHIC
GICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLL
FQELMAMNITPRLYTDR
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Description
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Functional site
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1)
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chain |
B |
| residue |
1163 |
| type |
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| sequence |
C
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| description |
binding site for residue ZN B 1301
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| source |
: AC4
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2)
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chain |
B |
| residue |
1166 |
| type |
|
| sequence |
C
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| description |
binding site for residue ZN B 1301
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| source |
: AC4
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3)
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chain |
B |
| residue |
1182 |
| type |
|
| sequence |
C
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| description |
binding site for residue ZN B 1301
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| source |
: AC4
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|
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4)
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chain |
B |
| residue |
1185 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN B 1301
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| source |
: AC4
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5)
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chain |
B |
| residue |
1185 |
| type |
BINDING |
| sequence |
C
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
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6)
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chain |
B |
| residue |
837 |
| type |
catalytic |
| sequence |
D
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| description |
788
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| source |
MCSA : MCSA1
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7)
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chain |
B |
| residue |
977-989 |
| type |
prosite |
| sequence |
GDKFASRHGQKGT
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| description |
RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
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| source |
prosite : PS01166
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