eF-site ID 6bfv-A PDB Code 6bfv Chain A click to enlarge Title Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one Classification TRANSFERASE Compound Purine nucleoside phosphorylase Source (A0A0U3AGT1_SCHMA) Sequence A:  VVANYENASMAADYIKRVSNVLPDIGIIXGSGLGKLIEEI EERKVIPYINIPNFPKTTVAGHVGNLVLGSVGGRKIVAMQ GRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINR KLKSGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDL SNAYDRLLQQLALKIAQENDFQDLVHEGVYAFNGGPTYES PDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIA NNSILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRL P Description Functional site 1) chain A residue 95 type sequence N description binding site for residue DMS A 301 source : AC1 2) chain A residue 96 type sequence Q description binding site for residue DMS A 301 source : AC1 3) chain A residue 99 type sequence A description binding site for residue DMS A 301 source : AC1 4) chain A residue 103 type sequence R description binding site for residue DMS A 301 source : AC1 5) chain A residue 148 type sequence V description binding site for residue DMS A 301 source : AC1 6) chain A residue 150 type sequence V description binding site for residue DMS A 301 source : AC1 7) chain A residue 28 type sequence D description binding site for residue DMS A 302 source : AC2 8) chain A residue 285 type sequence P description binding site for residue DMS A 302 source : AC2 9) chain A residue 161 type sequence F description binding site for residue DMS A 303 source : AC3 10) chain A residue 202 type sequence Y description binding site for residue DMS A 303 source : AC3 11) chain A residue 221 type sequence M description binding site for residue DMS A 303 source : AC3 12) chain A residue 259 type sequence H description binding site for residue DMS A 303 source : AC3 13) chain A residue 262 type sequence V description binding site for residue DMS A 303 source : AC3 14) chain A residue 162 type sequence P description binding site for residue DMS A 304 source : AC4 15) chain A residue 163 type sequence D description binding site for residue DMS A 304 source : AC4 16) chain A residue 231 type sequence C description binding site for residue DMS A 304 source : AC4 17) chain A residue 232 type sequence H description binding site for residue DMS A 304 source : AC4 18) chain A residue 91 type sequence E description binding site for residue DMS A 305 source : AC5 19) chain A residue 119 type sequence A description binding site for residue DJP A 306 source : AC6 20) chain A residue 120 type sequence G description binding site for residue DJP A 306 source : AC6 21) chain A residue 202 type sequence Y description binding site for residue DJP A 306 source : AC6 22) chain A residue 203 type sequence E description binding site for residue DJP A 306 source : AC6 23) chain A residue 220 type sequence G description binding site for residue DJP A 306 source : AC6 24) chain A residue 221 type sequence M description binding site for residue DJP A 306 source : AC6 25) chain A residue 244 type sequence A description binding site for residue DJP A 306 source : AC6 26) chain A residue 245 type sequence N description binding site for residue DJP A 306 source : AC6 27) chain A residue 262 type sequence V description binding site for residue DJP A 306 source : AC6

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