eF-site ID 6b5m-AHL PDB Code 6b5m Chain A, H, L click to enlarge Title Structure of PfCSP peptide 21 with human protective antibody CIS43 Classification IMMUNE SYSTEM Compound CIS43 Fab Heavy chain Source (6B5M) Sequence A:  NPDPNANPNVDPN H:  VQLVQSGAEVKKPGASVKVSCKASGYTFTSYAIHWVRQAP GQRLEWMGWIKAGNGNTRYSQKFQDRVTITRDTSTTTAYM ELSSLRSEDTAVYYCALLTVLTPDDAFDIWGQGTMVTVSS ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVS WNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQT YICNVNHKPSNTKVDKKVEP L:  DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLA WYQQKPGQPPNLLIYWASTRQSGVPDRFSGSGSGTDFTLT ISSLQAEDVAVYYCHQYYSSPLTFGGGTKVEIKRTVAAPS VFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYAC EVTHQGLSSPVTKSFNR Description (1)  CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 21 Functional site 1) chain H residue 52 type sequence K description binding site for residue SO4 H 301 source : AC1 2) chain H residue 54 type sequence N description binding site for residue SO4 H 301 source : AC1 3) chain L residue 211 type sequence R description binding site for residue SO4 H 301 source : AC1 4) chain L residue 8 type sequence P description binding site for residue SO4 L 301 source : AC2 5) chain L residue 9 type sequence D description binding site for residue SO4 L 301 source : AC2 6) chain L residue 10 type sequence S description binding site for residue SO4 L 301 source : AC2 7) chain H residue 123 type sequence P description binding site for residue SO4 L 302 source : AC3 8) chain L residue 121 type sequence S description binding site for residue SO4 L 302 source : AC3 9) chain L residue 122 type sequence D description binding site for residue SO4 L 302 source : AC3 10) chain L residue 123 type sequence E description binding site for residue SO4 L 302 source : AC3 11) chain L residue 103 type sequence K description binding site for residue SO4 L 303 source : AC4 12) chain L residue 105 type sequence E description binding site for residue SO4 L 303 source : AC4 13) chain L residue 142 type sequence R description binding site for residue SO4 L 303 source : AC4 14) chain L residue 114 type sequence S description binding site for residue EDO L 304 source : AC5 15) chain L residue 138 type sequence N description binding site for residue EDO L 304 source : AC5 16) chain H residue 194-200 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 17) chain L residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

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