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eF-site ID
|
6b3j-A |
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PDB Code
|
6b3j |
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Chain
|
A |
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click to enlarge
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Title
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3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex |
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Classification
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SIGNALING PROTEIN |
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Compound
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Glucagon-like peptide 1 receptor |
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Source
|
(6B3J) |
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Sequence
|
A: |
DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGSGI
FETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFV
VANRLQAALKLFDSIWNNKWLRDTSVILFLNKQDIEDYFP
EFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASG
DGRHYCYPHFTNIRRVFNDCRDIIQRMHLRQYELL
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Description
|
(1) |
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Nanobody 35, Calcitonin receptor
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Functional site
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|
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1)
|
chain |
A |
| residue |
223 |
| type |
MOD_RES |
| sequence |
D
|
| description |
N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378
|
| source |
Swiss-Prot : SWS_FT_FI1
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|
|
2)
|
chain |
A |
| residue |
292 |
| type |
MOD_RES |
| sequence |
N
|
| description |
N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378
|
| source |
Swiss-Prot : SWS_FT_FI1
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