eF-site ID 6b1c-C PDB Code 6b1c Chain C click to enlarge Title Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a) Classification ISOMERASE/ISOMERASE inhibitor Compound Macrophage migration inhibitory factor Source (MIF_HUMAN) Sequence C:  PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVH VVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLC GLLAERLRISPDRVYINYYDMNAANVGWNNSTFA Description Functional site 1) chain C residue 95 type sequence Y description binding site for residue C9J A 202 source : AC2 2) chain C residue 97 type sequence N description binding site for residue C9J A 202 source : AC2 3) chain C residue 16 type sequence D description binding site for residue SO4 C 201 source : AC4 4) chain C residue 17 type sequence G description binding site for residue SO4 C 201 source : AC4 5) chain C residue 18 type sequence F description binding site for residue SO4 C 201 source : AC4 6) chain C residue 19 type sequence L description binding site for residue SO4 C 201 source : AC4 7) chain C residue 20 type sequence S description binding site for residue SO4 C 201 source : AC4 8) chain C residue 68 type sequence G description binding site for residue SO4 C 202 source : AC5 9) chain C residue 69 type sequence G description binding site for residue SO4 C 202 source : AC5 10) chain C residue 70 type sequence A description binding site for residue SO4 C 202 source : AC5 11) chain C residue 71 type sequence Q description binding site for residue SO4 C 202 source : AC5 12) chain C residue 15 type sequence P description binding site for residue SO4 C 203 source : AC6 13) chain C residue 16 type sequence D description binding site for residue SO4 C 203 source : AC6 14) chain C residue 1 type ACT_SITE sequence P description Proton acceptor; via imino nitrogen => ECO:0000250|UniProtKB:P34884 source Swiss-Prot : SWS_FT_FI1 15) chain C residue 32 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 16) chain C residue 64 type BINDING sequence I description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 17) chain C residue 97 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 18) chain C residue 77 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P34884 source Swiss-Prot : SWS_FT_FI3

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