eF-site ID 6b1c-B PDB Code 6b1c Chain B click to enlarge Title Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a) Classification ISOMERASE/ISOMERASE inhibitor Compound Macrophage migration inhibitory factor Source (MIF_HUMAN) Sequence B:  PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVH VVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLC GLLAERLRISPDRVYINYYDMNAANVGWNNSTFA Description Functional site 1) chain B residue 92 type sequence D description binding site for residue C9J A 202 source : AC2 2) chain B residue 1 type sequence P description binding site for residue C9J B 201 source : AC3 3) chain B residue 2 type sequence M description binding site for residue C9J B 201 source : AC3 4) chain B residue 32 type sequence K description binding site for residue C9J B 201 source : AC3 5) chain B residue 36 type sequence Y description binding site for residue C9J B 201 source : AC3 6) chain B residue 62 type sequence H description binding site for residue C9J B 201 source : AC3 7) chain B residue 63 type sequence S description binding site for residue C9J B 201 source : AC3 8) chain B residue 64 type sequence I description binding site for residue C9J B 201 source : AC3 9) chain B residue 101 type sequence M description binding site for residue C9J B 201 source : AC3 10) chain B residue 106 type sequence V description binding site for residue C9J B 201 source : AC3 11) chain B residue 113 type sequence F description binding site for residue C9J B 201 source : AC3 12) chain B residue 1 type ACT_SITE sequence P description Proton acceptor; via imino nitrogen => ECO:0000250|UniProtKB:P34884 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 32 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 14) chain B residue 64 type BINDING sequence I description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 15) chain B residue 97 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11170644, ECO:0000269|PubMed:17526494, ECO:0000269|PubMed:19090677 source Swiss-Prot : SWS_FT_FI2 16) chain B residue 77 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P34884 source Swiss-Prot : SWS_FT_FI3

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