eF-site ID 6auu-B PDB Code 6auu Chain B click to enlarge Title Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-5-(trifluoromethyl)phenethyl)-4-methylpyridin-2-amine Classification OXIDOREDUCTASE Compound Nitric oxide synthase, brain Source (NOS1_RAT) Sequence B:  RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLP VRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKE IESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVF DARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTD GKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQ QGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIR HPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGW YMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKD QALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYR CRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQ PDPWNTHVWKG Description Functional site 1) chain B residue 676 type sequence W description binding site for residue H4B A 802 source : AC2 2) chain B residue 691 type sequence F description binding site for residue H4B A 802 source : AC2 3) chain B residue 692 type sequence H description binding site for residue H4B A 802 source : AC2 4) chain B residue 693 type sequence Q description binding site for residue H4B A 802 source : AC2 5) chain B residue 694 type sequence E description binding site for residue H4B A 802 source : AC2 6) chain B residue 326 type sequence C description binding site for residue ZN A 806 source : AC6 7) chain B residue 331 type sequence C description binding site for residue ZN A 806 source : AC6 8) chain B residue 409 type sequence W description binding site for residue HEM B 801 source : AC7 9) chain B residue 415 type sequence C description binding site for residue HEM B 801 source : AC7 10) chain B residue 457 type sequence S description binding site for residue HEM B 801 source : AC7 11) chain B residue 584 type sequence F description binding site for residue HEM B 801 source : AC7 12) chain B residue 585 type sequence S description binding site for residue HEM B 801 source : AC7 13) chain B residue 586 type sequence G description binding site for residue HEM B 801 source : AC7 14) chain B residue 587 type sequence W description binding site for residue HEM B 801 source : AC7 15) chain B residue 589 type sequence M description binding site for residue HEM B 801 source : AC7 16) chain B residue 592 type sequence E description binding site for residue HEM B 801 source : AC7 17) chain B residue 678 type sequence W description binding site for residue HEM B 801 source : AC7 18) chain B residue 704 type sequence F description binding site for residue HEM B 801 source : AC7 19) chain B residue 706 type sequence Y description binding site for residue HEM B 801 source : AC7 20) chain B residue 334 type sequence S description binding site for residue H4B B 802 source : AC8 21) chain B residue 336 type sequence M description binding site for residue H4B B 802 source : AC8 22) chain B residue 596 type sequence R description binding site for residue H4B B 802 source : AC8 23) chain B residue 677 type sequence V description binding site for residue H4B B 802 source : AC8 24) chain B residue 678 type sequence W description binding site for residue H4B B 802 source : AC8 25) chain B residue 478 type sequence Q description binding site for residue BY7 B 803 source : AC9 26) chain B residue 567 type sequence V description binding site for residue BY7 B 803 source : AC9 27) chain B residue 584 type sequence F description binding site for residue BY7 B 803 source : AC9 28) chain B residue 586 type sequence G description binding site for residue BY7 B 803 source : AC9 29) chain B residue 587 type sequence W description binding site for residue BY7 B 803 source : AC9 30) chain B residue 592 type sequence E description binding site for residue BY7 B 803 source : AC9 31) chain B residue 596 type sequence R description binding site for residue BY7 B 803 source : AC9 32) chain B residue 597 type sequence D description binding site for residue BY7 B 803 source : AC9 33) chain B residue 706 type sequence Y description binding site for residue BY7 B 803 source : AC9 34) chain B residue 587 type sequence W description binding site for residue ACT B 804 source : AD1 35) chain B residue 649 type sequence V description binding site for residue ACT B 804 source : AD1 36) chain B residue 477 type sequence S description binding site for residue MTL B 805 source : AD2 37) chain B residue 481 type sequence R description binding site for residue MTL B 805 source : AD2 38) chain B residue 497 type sequence A description binding site for residue MTL B 805 source : AD2 39) chain B residue 498 type sequence N description binding site for residue MTL B 805 source : AD2 40) chain B residue 500 type sequence Q description binding site for residue MTL B 805 source : AD2 41) chain B residue 501 type sequence F description binding site for residue MTL B 805 source : AD2 42) chain B residue 569 type sequence N description binding site for residue MTL B 805 source : AD2 43) chain B residue 709 type sequence D description binding site for residue MTL B 805 source : AD2 44) chain B residue 711 type sequence W description binding site for residue MTL B 805 source : AD2 45) chain B residue 588 type sequence Y description binding site for residue CL B 806 source : AD3 46) chain B residue 597 type sequence D description binding site for residue CL B 806 source : AD3 47) chain B residue 415 type BINDING sequence C description axial binding residue => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI2 48) chain B residue 334 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 49) chain B residue 478 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 50) chain B residue 587 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 51) chain B residue 588 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 52) chain B residue 592 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 53) chain B residue 677 type BINDING sequence V description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 54) chain B residue 678 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 55) chain B residue 691 type BINDING sequence F description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 56) chain B residue 706 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links