eF-site ID 6akh-ADPT PDB Code 6akh Chain A, D, P, T click to enlarge Title Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Mn-dUMPNPP Classification TRANSFERASE/DNA Compound DNA-directed DNA/RNA polymerase mu Source (6AKH) Sequence A:  MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLL TFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELL EHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYRE GLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDA LQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITH PKEGQEAGLLPRVMCRLQDQGLILYHQHAFERSFCIFRLP QPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRF SRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYL PPEQRNA D:  GCCG P:  CGTA T:  CGGCATACG Description Functional site 1) chain A residue 149 type sequence L description binding site for residue EPE A 501 source : AC1 2) chain A residue 325 type sequence K description binding site for residue EPE A 501 source : AC1 3) chain A residue 326 type sequence L description binding site for residue EPE A 501 source : AC1 4) chain A residue 327 type sequence Q description binding site for residue EPE A 501 source : AC1 5) chain A residue 330 type sequence D description binding site for residue MN A 502 source : AC2 6) chain A residue 332 type sequence D description binding site for residue MN A 502 source : AC2 7) chain A residue 330 type sequence D description binding site for residue MN A 503 source : AC3 8) chain A residue 332 type sequence D description binding site for residue MN A 503 source : AC3 9) chain A residue 418 type sequence D description binding site for residue MN A 503 source : AC3 10) chain P residue 4 type sequence A description binding site for residue MN A 503 source : AC3 11) chain A residue 241 type sequence T description binding site for residue NA A 504 source : AC4 12) chain A residue 243 type sequence I description binding site for residue NA A 504 source : AC4 13) chain A residue 246 type sequence V description binding site for residue NA A 504 source : AC4 14) chain P residue 3 type sequence T description binding site for residue NA A 504 source : AC4 15) chain A residue 319 type sequence G description binding site for residue DUP A 505 source : AC5 16) chain A residue 320 type sequence G description binding site for residue DUP A 505 source : AC5 17) chain A residue 323 type sequence R description binding site for residue DUP A 505 source : AC5 18) chain A residue 325 type sequence K description binding site for residue DUP A 505 source : AC5 19) chain A residue 328 type sequence G description binding site for residue DUP A 505 source : AC5 20) chain A residue 329 type sequence H description binding site for residue DUP A 505 source : AC5 21) chain A residue 330 type sequence D description binding site for residue DUP A 505 source : AC5 22) chain A residue 332 type sequence D description binding site for residue DUP A 505 source : AC5 23) chain A residue 433 type sequence G description binding site for residue DUP A 505 source : AC5 24) chain A residue 434 type sequence W description binding site for residue DUP A 505 source : AC5 25) chain A residue 436 type sequence G description binding site for residue DUP A 505 source : AC5 26) chain A residue 438 type sequence K description binding site for residue DUP A 505 source : AC5 27) chain P residue 4 type sequence A description binding site for residue DUP A 505 source : AC5 28) chain T residue 5 type sequence A description binding site for residue DUP A 505 source : AC5 29) chain A residue 190 type sequence P description binding site for residue EDO A 506 source : AC6 30) chain A residue 191 type sequence S description binding site for residue EDO A 506 source : AC6 31) chain A residue 192 type sequence P description binding site for residue EDO A 506 source : AC6 32) chain A residue 198 type sequence Q description binding site for residue EDO A 506 source : AC6 33) chain A residue 387 type sequence R description binding site for residue EDO A 507 source : AC7 34) chain A residue 433 type sequence G description binding site for residue EDO A 507 source : AC7 35) chain A residue 434 type sequence W description binding site for residue EDO A 507 source : AC7 36) chain A residue 445 type sequence R description binding site for residue EDO A 507 source : AC7 37) chain P residue 4 type sequence A description binding site for residue EDO A 507 source : AC7 38) chain A residue 438 type sequence K description binding site for residue EDO A 508 source : AC8 39) chain A residue 442 type sequence R description binding site for residue EDO A 508 source : AC8 40) chain A residue 144 type sequence Q description binding site for residue EDO A 510 source : AD1 41) chain D residue 4 type sequence G description binding site for residue EDO A 510 source : AD1 42) chain A residue 387 type sequence R description binding site for residue EDO A 511 source : AD2 43) chain A residue 445 type sequence R description binding site for residue EDO A 511 source : AD2 44) chain A residue 457 type sequence N description binding site for residue EDO A 511 source : AD2 45) chain A residue 458 type sequence S description binding site for residue EDO A 511 source : AD2 46) chain T residue 6 type sequence T description binding site for residue EDO A 511 source : AD2 47) chain T residue 7 type sequence A description binding site for residue EDO A 511 source : AD2 48) chain D residue 2 type sequence C description binding site for residue EDO T 101 source : AD3 49) chain T residue 1 type sequence C description binding site for residue EDO T 101 source : AD3 50) chain T residue 2 type sequence G description binding site for residue EDO T 101 source : AD3 51) chain A residue 319-338 type prosite sequence GGFRRGKLQGHDVDFLITHP description DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP source prosite : PS00522 52) chain A residue 330 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 53) chain A residue 332 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 54) chain A residue 418 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 55) chain A residue 433 type SITE sequence G description Responsible for the low discrimination between dNTP and rNTP source Swiss-Prot : SWS_FT_FI2

Display surface Download Links