eF-site ID 6ah4-C PDB Code 6ah4 Chain C click to enlarge Title Structure of human P2X3 receptor in complex with ATP and Ca2+ ion Classification MEMBRANE PROTEIN Compound P2X purinoceptor 3 Source (P2RX3_HUMAN) Sequence C:  FFTYETPKVIVVKSWTIGIINRVVQLLIISYFVGWVFLHE KAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQG TSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPER LPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMM EAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFH PDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWV CDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYY KMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSV AAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNE Description (1)  P2X purinoceptor 3 Functional site 1) chain C residue 21-43 type TRANSMEM sequence WTIGIINRVVQLLIISYFVGWVF description Helical; Name=1 => ECO:0000269|PubMed:27626375 source Swiss-Prot : SWS_FT_FI1 2) chain C residue 44-322 type TOPO_DOM sequence LHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTP PQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCG PERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETP IMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTC RFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKI GWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFA KYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTI description Extracellular => ECO:0000269|PubMed:27626375 source Swiss-Prot : SWS_FT_FI2 3) chain C residue 323-341 type TRANSMEM sequence ISSVAAFTSVGVGTVLCDI description Helical; Name=2 => ECO:0000269|PubMed:27626375 source Swiss-Prot : SWS_FT_FI3 4) chain C residue 63 type BINDING sequence K description BINDING => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP source Swiss-Prot : SWS_FT_FI4 5) chain C residue 172 type BINDING sequence T description BINDING => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP source Swiss-Prot : SWS_FT_FI4 6) chain C residue 275 type BINDING sequence S description BINDING => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP source Swiss-Prot : SWS_FT_FI4 7) chain C residue 279 type BINDING sequence N description BINDING => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP source Swiss-Prot : SWS_FT_FI4 8) chain C residue 299 type BINDING sequence K description BINDING => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP source Swiss-Prot : SWS_FT_FI4 9) chain C residue 139 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVK source Swiss-Prot : SWS_FT_FI5 10) chain C residue 170 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVJ, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP, ECO:0007744|PDB:5SVQ, ECO:0007744|PDB:5SVR, ECO:0007744|PDB:5SVS, ECO:0007744|PDB:5SVT source Swiss-Prot : SWS_FT_FI6 11) chain C residue 290 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVJ, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP, ECO:0007744|PDB:5SVQ, ECO:0007744|PDB:5SVR, ECO:0007744|PDB:5SVS, ECO:0007744|PDB:5SVT source Swiss-Prot : SWS_FT_FI6 12) chain C residue 194 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:27626375, ECO:0007744|PDB:5SVJ, ECO:0007744|PDB:5SVK, ECO:0007744|PDB:5SVL, ECO:0007744|PDB:5SVM, ECO:0007744|PDB:5SVP, ECO:0007744|PDB:5SVQ, ECO:0007744|PDB:5SVS, ECO:0007744|PDB:5SVT source Swiss-Prot : SWS_FT_FI7

Display surface Download Links