eF-site ID 6a6n-A PDB Code 6a6n Chain A click to enlarge Title Crystal structure of an inward-open apo state of the eukaryotic ABC multidrug transporter CmABCB1 Classification TRANSPORT PROTEIN Compound ATP-binding cassette, sub-family B, member 1 Source (M1VAN7_CYAM1) Sequence A:  TGVTARRIFALAWSSSATMIVIGFIASILEGATLPAFAIV FGRMFAVFTKSKSQIEGETWKYSVGFVGIGVFEFIVAGSR TALFGIASERLARDLRVAAFSNLVEQDVTYFDRRKAGELG GKLNNDVQVIQYSFSKLGAVLFNLAQCVVGIIVAFIFAPA LTGVLIALSPLVVLAGAAQMIEMSGNTKRSSEAYASAGSV AAEVFSNIRTTKAFEAERYETQRYGSKLDPLYRLGRRRYI SDGLFFGLSMLVIFCVYALALWWGGQLIARGSLNLGNLLA AFFSAILGFMGVGQAAQVWPDVTRGLGAGGELFAMIDRVP QYRRPDPGAEVVTQPLVLKQGIVFENVHFRYPTRMNVEVL RGISLTIPNGKTVAIVGGSGAGKSTIIQLLMRFYDIEPQG GGLLLFDGTPAWNYDFHALRSQIGLVSQEPVLFSGTIRDN ILYGKRDATDEEVIQALREANAYSFVMALPDGLDTEVGER GLALSGGQKQRIAIARAILKHPTLLCLDESTSALDAESEA LVQEALDRMMASDGVTSVVIAHRLSTVARADLILVMQDGV VVEQGNHSELMALGPSGFYYQLVEKQL Description Functional site 1) chain A residue 119 type sequence T description binding site for residue DMU A 801 source : AC1 2) chain A residue 122 type sequence V description binding site for residue DMU A 801 source : AC1 3) chain A residue 451 type sequence R description binding site for residue DMU A 801 source : AC1 4) chain A residue 456 type sequence M description binding site for residue DMU A 801 source : AC1 5) chain A residue 500 type sequence Q description binding site for residue DMU A 801 source : AC1 6) chain A residue 111 type sequence A description binding site for residue DMU A 802 source : AC2 7) chain A residue 114 type sequence W description binding site for residue DMU A 802 source : AC2 8) chain A residue 498 type sequence E description binding site for residue DMU A 802 source : AC2 9) chain A residue 179 type sequence G description binding site for residue DMU A 804 source : AC3 10) chain A residue 184 type sequence L description binding site for residue DMU A 804 source : AC3 11) chain A residue 471 type sequence G description binding site for residue TRS A 805 source : AC4 12) chain A residue 631 type sequence M description binding site for residue TRS A 805 source : AC4 13) chain A residue 632 type sequence A description binding site for residue TRS A 805 source : AC4 14) chain A residue 633 type sequence S description binding site for residue TRS A 805 source : AC4 15) chain A residue 652 type sequence D description binding site for residue TRS A 805 source : AC4 16) chain A residue 585-599 type prosite sequence LSGGQKQRIAIARAI description ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQKQRIAIARAI source prosite : PS00211

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