eF-site ID 6a5y-D PDB Code 6a5y Chain D click to enlarge Title Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC143 and 9cRA and SRC1 Classification TRANSCRIPTION Compound Bile acid receptor Source (RXRA_HUMAN) Sequence D:  EDMPVERILEAELAVEDPVTNICQAADKQLFTLVEWAKRI PHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILL ATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTE LGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKH KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP IDTFLMEMLEA Description Functional site 1) chain D residue 268 type sequence I description binding site for residue 9CR D 501 source : AC3 2) chain D residue 271 type sequence A description binding site for residue 9CR D 501 source : AC3 3) chain D residue 275 type sequence Q description binding site for residue 9CR D 501 source : AC3 4) chain D residue 305 type sequence W description binding site for residue 9CR D 501 source : AC3 5) chain D residue 313 type sequence F description binding site for residue 9CR D 501 source : AC3 6) chain D residue 316 type sequence R description binding site for residue 9CR D 501 source : AC3 7) chain D residue 326 type sequence L description binding site for residue 9CR D 501 source : AC3 8) chain D residue 327 type sequence A description binding site for residue 9CR D 501 source : AC3 9) chain D residue 345 type sequence I description binding site for residue 9CR D 501 source : AC3 10) chain D residue 432 type sequence C description binding site for residue 9CR D 501 source : AC3 11) chain D residue 411 type sequence Q description binding site for residue PO4 D 502 source : AC4 12) chain D residue 412 type sequence P description binding site for residue PO4 D 502 source : AC4 13) chain D residue 413 type sequence G description binding site for residue PO4 D 502 source : AC4 14) chain D residue 414 type sequence R description binding site for residue PO4 D 502 source : AC4 15) chain D residue 417 type sequence K description binding site for residue PO4 D 502 source : AC4 16) chain D residue 348 type sequence R description binding site for residue SO4 D 503 source : AC5 17) chain D residue 427 type sequence S description binding site for residue SO4 D 503 source : AC5

Display surface Download Links