eF-site ID 5zy9-CDE PDB Code 5zy9 Chain C, D, E click to enlarge Title Structural basis for a tRNA synthetase Classification LIGASE Compound Threonyl-tRNA synthase Source (G3FIN0_PHYSO) Sequence C:  MDHRRLGVSEELFFFHSLSPGSGFWLPHGSAIYFKLLKFI REQYRARGYTEVITPNIFNMELWNISGHAKHYKENMFVFD VEGQEYALKPMNCPAASLMFDFRQRSYRELPIRYADCGVL HRNELSGALTGLTRVRRFQQDDAHIFCRDDQIKKEVLDFL SFMKYVYDVFGIEFNLELSTRPEKAMGELEQWERAESQLA EALDEFVGAGKWVVNPGDGAFYGPKIDIMITDALKRQHQC ATVQLDFQLPIRFNLKYRTDDADNFKRPVIIHRAIYGSLE RFVAVLVEHYAGKFPFWLSPRQVLIVTVGAAFVDYGYEVK DAMFRAGFDVDIDDTGKTLNKKIREGQMAHYNFILVVGAH EKETRSVNIRTRDNKVTGTKTLEEAIAMFKELEETKAADE D:  MDHRRLGVSEELFFFHSLSPGSGFWLPHGSAIYFKLLKFI REQYRARGYTEVITPNIFNMELWNISGHAKHYKENMFVFD VEGQEYALKPMNCPAASLMFDFRQRSYRELPIRYADCGVL HRNELSGALTGLTRVRRFQQDDAHIFCRDDQIKKEVLDFL SFMKYVYDVFGIEFNLELSTRPEKAMGELEQWERAESQLA EALDEFVGAGKWVVNPGDGAFYGPKIDIMITDALKRQHQC ATVQLDFQLPIRFNLKYRTDDADNFKRPVIIHRAIYGSLE RFVAVLVEHYAGKFPFWLSPRQVLIVTVGAAFVDYGYEVK DAMFRAGFDVDIDDTGKTLNKKIREGQMAHYNFILVVGAH EKETRSVNIRTRDNKVTGTKTLEEAIAMFKELEETKAADE E:  HRRLGVSEELFFFHSLSPGSGFWLPHGSAIYFKLLKFIRE QYRARGYTEVITPNIFNMELWNISGHAKHYKENMFVFDVE GQEYALKPMNCPAASLMFDFRQRSYRELPIRYADCGVLHR NELSGALTGLTRVRRFQQDDAHIFCRDDQIKKEVLDFLSF MKYVYDVFGIEFNLELSTRPEKAMGELEQWERAESQLAEA LDEFVGAGKWVVNPGDGAFYGPKIDIMITDALKRQHQCAT VQLDFQLPIRFNLKYRTDDADNFKRPVIIHRAIYGSLERF VAVLVEHYAGKFPFWLSPRQVLIVTVGAAFVDYGYEVKDA MFRAGFDVDIDDTGKTLNKKIREGQMAHYNFILVVGAHEK ETRSVNIRTRDNKVTGTKTLEEAIAMFKELEETKAADE Description Functional site 1) chain C residue 67 type sequence G description binding site for residue 2CR C 501 source : AC1 2) chain C residue 68 type sequence H description binding site for residue 2CR C 501 source : AC1 3) chain C residue 91 type sequence M description binding site for residue 2CR C 501 source : AC1 4) chain C residue 122 type sequence R description binding site for residue 2CR C 501 source : AC1 5) chain C residue 140 type sequence Q description binding site for residue 2CR C 501 source : AC1 6) chain C residue 222 type sequence Y description binding site for residue 2CR C 501 source : AC1 7) chain C residue 246 type sequence D description binding site for residue 2CR C 501 source : AC1 8) chain C residue 249 type sequence L description binding site for residue 2CR C 501 source : AC1 9) chain C residue 93 type sequence C description binding site for residue ZN C 502 source : AC2 10) chain C residue 144 type sequence H description binding site for residue ZN C 502 source : AC2 11) chain C residue 272 type sequence H description binding site for residue ZN C 502 source : AC2 12) chain D residue 67 type sequence G description binding site for residue 2CR D 501 source : AC3 13) chain D residue 68 type sequence H description binding site for residue 2CR D 501 source : AC3 14) chain D residue 91 type sequence M description binding site for residue 2CR D 501 source : AC3 15) chain D residue 122 type sequence R description binding site for residue 2CR D 501 source : AC3 16) chain D residue 140 type sequence Q description binding site for residue 2CR D 501 source : AC3 17) chain D residue 222 type sequence Y description binding site for residue 2CR D 501 source : AC3 18) chain D residue 246 type sequence D description binding site for residue 2CR D 501 source : AC3 19) chain D residue 249 type sequence L description binding site for residue 2CR D 501 source : AC3 20) chain D residue 272 type sequence H description binding site for residue 2CR D 501 source : AC3 21) chain D residue 93 type sequence C description binding site for residue ZN D 502 source : AC4 22) chain D residue 144 type sequence H description binding site for residue ZN D 502 source : AC4 23) chain D residue 272 type sequence H description binding site for residue ZN D 502 source : AC4 24) chain E residue 67 type sequence G description binding site for residue 2CR E 801 source : AC5 25) chain E residue 68 type sequence H description binding site for residue 2CR E 801 source : AC5 26) chain E residue 91 type sequence M description binding site for residue 2CR E 801 source : AC5 27) chain E residue 122 type sequence R description binding site for residue 2CR E 801 source : AC5 28) chain E residue 140 type sequence Q description binding site for residue 2CR E 801 source : AC5 29) chain E residue 222 type sequence Y description binding site for residue 2CR E 801 source : AC5 30) chain E residue 246 type sequence D description binding site for residue 2CR E 801 source : AC5 31) chain E residue 248 type sequence Q description binding site for residue 2CR E 801 source : AC5 32) chain E residue 249 type sequence L description binding site for residue 2CR E 801 source : AC5 33) chain E residue 272 type sequence H description binding site for residue 2CR E 801 source : AC5 34) chain E residue 93 type sequence C description binding site for residue ZN E 802 source : AC6 35) chain E residue 144 type sequence H description binding site for residue ZN E 802 source : AC6 36) chain E residue 272 type sequence H description binding site for residue ZN E 802 source : AC6

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