eF-site ID 5zy6-B PDB Code 5zy6 Chain B click to enlarge Title catechol methyltransferase spCOMT Classification TRANSFERASE Compound Probable catechol O-methyltransferase 1 Source (COMT1_SCHPO) Sequence B:  EKEQLFLQHIQNLPQERLDAIRGHPELVLKEIDEFTYPDG SGVRMCIGDVKGGFIVGKIRERKPKIMVELGGYLGYSAIL FGNEISKIPGGRYYSLEVNEDYAKIAYELVKLAGLDEIVT IMIGKACDSLVELQQKLLHKDLGFQALDMVFIDHWKDLYV PDLRVIESLNMIAPGTLLVADNIITPGAPEYHKYVNMSPE ERRGYQAKVRNVNGFDFIGRWDLIYKTETKEFEDAVDVTE CVGYA Description Functional site 1) chain B residue 54 type sequence M description binding site for residue SAM B 301 source : AC2 2) chain B residue 56 type sequence I description binding site for residue SAM B 301 source : AC2 3) chain B residue 80 type sequence G description binding site for residue SAM B 301 source : AC2 4) chain B residue 81 type sequence G description binding site for residue SAM B 301 source : AC2 5) chain B residue 82 type sequence Y description binding site for residue SAM B 301 source : AC2 6) chain B residue 85 type sequence Y description binding site for residue SAM B 301 source : AC2 7) chain B residue 86 type sequence S description binding site for residue SAM B 301 source : AC2 8) chain B residue 105 type sequence L description binding site for residue SAM B 301 source : AC2 9) chain B residue 106 type sequence E description binding site for residue SAM B 301 source : AC2 10) chain B residue 107 type sequence V description binding site for residue SAM B 301 source : AC2 11) chain B residue 111 type sequence Y description binding site for residue SAM B 301 source : AC2 12) chain B residue 135 type sequence A description binding site for residue SAM B 301 source : AC2 13) chain B residue 162 type sequence D description binding site for residue SAM B 301 source : AC2 14) chain B residue 163 type sequence H description binding site for residue SAM B 301 source : AC2 15) chain B residue 164 type sequence W description binding site for residue SAM B 301 source : AC2 16) chain B residue 167 type sequence L description binding site for residue SAM B 301 source : AC2 17) chain B residue 86 type BINDING sequence S description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 106 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 107 type BINDING sequence V description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 135 type BINDING sequence A description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 162 type BINDING sequence D description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 56 type BINDING sequence I description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 78 type BINDING sequence E description BINDING => ECO:0000255|PROSITE-ProRule:PRU01019 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 165 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 25) chain B residue 190 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 191 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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