eF-site ID 5zx3-D PDB Code 5zx3 Chain D click to enlarge Title Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H Classification TRANSCRIPTION Compound DNA-directed RNA polymerase subunit alpha Source (SIGH_MYCTU) Sequence D:  LDVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKP EKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVE VTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLA PKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKA VEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGG EREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLY RELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVI RNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIP PELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLG APEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKS LSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQC GLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRP QVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKA IQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLS SNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQP ASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLR PPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGY PFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGF YWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQ RGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIIT IVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFR EGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVS QDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAY ARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVK VRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQ SIGEPGTQLTTGGLPRVQELFEARVPRGKAPIADVTGRVR LEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDG SERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHL VREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTE FLPGSLIDRAEFEAENAAGRPVLMGITKASLATDSWLSAA SFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGI NRYRNIAVQPTEEARAA Description Functional site 1) chain D residue 891 type sequence C description binding site for residue ZN D 2001 source : AC1 2) chain D residue 963 type sequence R description binding site for residue ZN D 2001 source : AC1 3) chain D residue 968 type sequence C description binding site for residue ZN D 2001 source : AC1 4) chain D residue 975 type sequence C description binding site for residue ZN D 2001 source : AC1 5) chain D residue 978 type sequence C description binding site for residue ZN D 2001 source : AC1 6) chain D residue 60 type sequence C description binding site for residue ZN D 2002 source : AC2 7) chain D residue 62 type sequence C description binding site for residue ZN D 2002 source : AC2 8) chain D residue 75 type sequence C description binding site for residue ZN D 2002 source : AC2 9) chain D residue 78 type sequence C description binding site for residue ZN D 2002 source : AC2 10) chain D residue 975 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 11) chain D residue 978 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 12) chain D residue 62 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 13) chain D residue 75 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 14) chain D residue 78 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain D residue 535 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 16) chain D residue 537 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 17) chain D residue 539 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 18) chain D residue 891 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 19) chain D residue 968 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links