eF-site ID 5zx2-D PDB Code 5zx2 Chain D click to enlarge Title Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA Classification TRANSCRIPTION/DNA/RNA Compound DNA-directed RNA polymerase subunit alpha Source (5ZX2) Sequence D:  DVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPE KDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEV TRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAP KDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAV EDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGE REMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYR ELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIR NGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPP ELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGA PEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSL SDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCG LPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQ VWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAI QLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSS NNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPA SGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRP PVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYP FVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFY WATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQR GALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITI VDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFRE GLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQ DVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYA RTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKV RSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQS IGEPGTQLTGGLPRVQELFEARVPRGKAPIADVTGRVRLE DGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSE RVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVR EVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFL PGSLIDRAEFEAENRRVEPAAGRPVLMGITKASLATDSWL SAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAG TGINRYRNIAVQPTEEARAA Description Functional site 1) chain D residue 60 type sequence C description binding site for residue ZN D 2001 source : AC1 2) chain D residue 62 type sequence C description binding site for residue ZN D 2001 source : AC1 3) chain D residue 75 type sequence C description binding site for residue ZN D 2001 source : AC1 4) chain D residue 78 type sequence C description binding site for residue ZN D 2001 source : AC1 5) chain D residue 891 type sequence C description binding site for residue ZN D 2002 source : AC2 6) chain D residue 968 type sequence C description binding site for residue ZN D 2002 source : AC2 7) chain D residue 975 type sequence C description binding site for residue ZN D 2002 source : AC2 8) chain D residue 978 type sequence C description binding site for residue ZN D 2002 source : AC2 9) chain D residue 975 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 10) chain D residue 978 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 11) chain D residue 535 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 12) chain D residue 537 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 13) chain D residue 539 type DNA_BIND sequence D description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 14) chain D residue 891 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain D residue 968 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 16) chain D residue 62 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 17) chain D residue 75 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 18) chain D residue 78 type DNA_BIND sequence C description H-T-H motif => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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