eF-site ID 5zni-A PDB Code 5zni Chain A click to enlarge Title Plasmodium falciparum purine nucleoside phosphorylase in complex with mefloquine Classification TRANSFERASE Compound Purine nucleoside phosphorylase Source (Q8T9Z7_PLAFA) Sequence A:  NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLA YNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNG AKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLI HGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYP NKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGI LIVDGCPFKHQLENMIKIALGACAKLATKYA Description Functional site 1) chain A residue 23 type sequence G description binding site for residue PO4 A 301 source : AC1 2) chain A residue 27 type sequence R description binding site for residue PO4 A 301 source : AC1 3) chain A residue 45 type sequence R description binding site for residue PO4 A 301 source : AC1 4) chain A residue 88 type sequence R description binding site for residue PO4 A 301 source : AC1 5) chain A residue 90 type sequence G description binding site for residue PO4 A 301 source : AC1 6) chain A residue 91 type sequence S description binding site for residue PO4 A 301 source : AC1 7) chain A residue 7 type sequence H description binding site for residue YMZ A 302 source : AC2 8) chain A residue 45 type sequence R description binding site for residue YMZ A 302 source : AC2 9) chain A residue 92 type sequence C description binding site for residue YMZ A 302 source : AC2 10) chain A residue 93 type sequence G description binding site for residue YMZ A 302 source : AC2 11) chain A residue 160 type sequence Y description binding site for residue YMZ A 302 source : AC2 12) chain A residue 181 type sequence V description binding site for residue YMZ A 302 source : AC2 13) chain A residue 182 type sequence E description binding site for residue YMZ A 302 source : AC2 14) chain A residue 183 type sequence M description binding site for residue YMZ A 302 source : AC2 15) chain A residue 206 type sequence D description binding site for residue YMZ A 302 source : AC2 16) chain A residue 207 type sequence G description binding site for residue YMZ A 302 source : AC2 17) chain A residue 208 type sequence C description binding site for residue YMZ A 302 source : AC2 18) chain A residue 209 type sequence P description binding site for residue YMZ A 302 source : AC2

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