eF-site ID 5zkp-A PDB Code 5zkp Chain A click to enlarge Title Crystal structure of the human platelet-activating factor receptor in complex with SR 27417 Classification SIGNALING PROTEIN Compound Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor Source (PTAFR_HUMAN) Sequence A:  SSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYP CKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWIL PKFLCNVAGCLFFINTYCSVAFLGVITYNRYQAVTRPISL VIWVAIVGAASYFLILDSTNTVPDSAGSGDVTRCFEHYEK GSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQAKA LIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAG GLFEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQ GRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGAEIVQDGL RIDGDPRAARDDIVGWAHDVRGAIAEVKRRDLWMACTVLA VFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTL CLLSTNCVLNPVIYCFLTKKFRKHLTEKFYSMRSSR Description Functional site 1) chain A residue 22 type sequence Y description binding site for residue 9ER A 1201 source : AC1 2) chain A residue 73 type sequence W description binding site for residue 9ER A 1201 source : AC1 3) chain A residue 77 type sequence Y description binding site for residue 9ER A 1201 source : AC1 4) chain A residue 94 type sequence G description binding site for residue 9ER A 1201 source : AC1 5) chain A residue 97 type sequence F description binding site for residue 9ER A 1201 source : AC1 6) chain A residue 98 type sequence F description binding site for residue 9ER A 1201 source : AC1 7) chain A residue 102 type sequence Y description binding site for residue 9ER A 1201 source : AC1 8) chain A residue 174 type sequence F description binding site for residue 9ER A 1201 source : AC1 9) chain A residue 191 type sequence I description binding site for residue 9ER A 1201 source : AC1 10) chain A residue 255 type sequence W description binding site for residue 9ER A 1201 source : AC1 11) chain A residue 275 type sequence H description binding site for residue 9ER A 1201 source : AC1 12) chain A residue 279 type sequence L description binding site for residue 9ER A 1201 source : AC1 13) chain A residue 51 type sequence E description binding site for residue FMN A 1202 source : AC2 14) chain A residue 1009 type sequence S description binding site for residue FMN A 1202 source : AC2 15) chain A residue 1010 type sequence T description binding site for residue FMN A 1202 source : AC2 16) chain A residue 1011 type sequence T description binding site for residue FMN A 1202 source : AC2 17) chain A residue 1012 type sequence G description binding site for residue FMN A 1202 source : AC2 18) chain A residue 1013 type sequence N description binding site for residue FMN A 1202 source : AC2 19) chain A residue 1014 type sequence T description binding site for residue FMN A 1202 source : AC2 20) chain A residue 1057 type sequence S description binding site for residue FMN A 1202 source : AC2 21) chain A residue 1058 type sequence T description binding site for residue FMN A 1202 source : AC2 22) chain A residue 1059 type sequence W description binding site for residue FMN A 1202 source : AC2 23) chain A residue 1060 type sequence G description binding site for residue FMN A 1202 source : AC2 24) chain A residue 1092 type sequence C description binding site for residue FMN A 1202 source : AC2 25) chain A residue 1093 type sequence G description binding site for residue FMN A 1202 source : AC2 26) chain A residue 1094 type sequence D description binding site for residue FMN A 1202 source : AC2 27) chain A residue 1097 type sequence W description binding site for residue FMN A 1202 source : AC2 28) chain A residue 1099 type sequence Y description binding site for residue FMN A 1202 source : AC2 29) chain A residue 1100 type sequence F description binding site for residue FMN A 1202 source : AC2 30) chain A residue 1101 type sequence C description binding site for residue FMN A 1202 source : AC2 31) chain A residue 1127 type sequence G description binding site for residue FMN A 1202 source : AC2 32) chain A residue 17-38 type TRANSMEM sequence LFPIVYSIIFVLGVIANGYVLW description Helical; Name=1 => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 169 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI10 34) chain A residue 39-54 type TOPO_DOM sequence VFARLYPCKKFNEIKI description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 35) chain A residue 55-74 type TRANSMEM sequence FMVNLTMADMLFLITLPLWI description Helical; Name=2 => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 36) chain A residue 75-91 type TOPO_DOM sequence VYYQNQGNWILPKFLCN description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 37) chain A residue 156-184 type TOPO_DOM sequence DSTNTVPDSAGSGDVTRCFEHYEKGSVPV description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 38) chain A residue 255-276 type TOPO_DOM sequence WTLAELGFQDSKFHQAINDAHQ description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 39) chain A residue 92-113 type TRANSMEM sequence VAGCLFFINTYCSVAFLGVITY description Helical; Name=3 => ECO:0000255 source Swiss-Prot : SWS_FT_FI5 40) chain A residue 185-205 type TRANSMEM sequence LIIHIFIVFSFFLVFLIILFC description Helical; Name=5 => ECO:0000255 source Swiss-Prot : SWS_FT_FI7 41) chain A residue 234-254 type TRANSMEM sequence ACTVLAVFIICFVPHHVVQLP description Helical; Name=6 => ECO:0000255 source Swiss-Prot : SWS_FT_FI8 42) chain A residue 277-296 type TRANSMEM sequence VTLCLLSTNCVLNPVIYCFL description Helical; Name=7 => ECO:0000255 source Swiss-Prot : SWS_FT_FI9 43) chain A residue 1005-1021 type prosite sequence IVYGSTTGNTEYTAETI description FLAVODOXIN Flavodoxin signature. IVYgSTtGnTEytAEtI source prosite : PS00201 44) chain A residue 103-119 type prosite sequence CSVAFLGVITYNRYQAV description G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. CSVaFLGVITYNRYQaV source prosite : PS00237

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