eF-site ID 5zhx-B PDB Code 5zhx Chain B click to enlarge Title Crystal structure of SmgGDS-558 and farnesylated RhoA complex Classification ONCOPROTEIN Compound Rap1 GTPase-GDP dissociation stimulator 1 Source (RHOA_HUMAN) Sequence B:  DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQ LINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESS KEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAEND AIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDL MVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLA GALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNV TVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEM PPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCE AKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHL VTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLV QILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDL AFLDVVSKLRSHENKSVAQQASLTEQRLT Description (1)  Rap1 GTPase-GDP dissociation stimulator 1 Functional site 1) chain B residue 118 type sequence Y description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 2) chain B residue 124 type sequence Q description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 3) chain B residue 136 type sequence L description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 4) chain B residue 139 type sequence L description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 5) chain B residue 152 type sequence M description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 6) chain B residue 153 type sequence C description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2 7) chain B residue 155 type sequence V description binding site for Di-peptide FAR f 201 and CYS f 190 source : AC2

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