eF-site ID 5zg2-B PDB Code 5zg2 Chain B click to enlarge Title Crystal structure of the GluA2o LBD in complex with ZK200775 and Compound-2 Classification TRANSPORT PROTEIN Compound Glutamate receptor 2 Source (GRIA2_HUMAN) Sequence B:  KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEI AKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKA DIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIES AEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMR SAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR KPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNE QGLLDKLKNKWWYDKGECG Description Functional site 1) chain B residue 502 type sequence I description binding site for residue 9C0 A 902 source : AC2 2) chain B residue 514 type sequence K description binding site for residue 9C0 A 902 source : AC2 3) chain B residue 515 type sequence P description binding site for residue 9C0 A 902 source : AC2 4) chain B residue 518 type sequence S description binding site for residue 9C0 A 902 source : AC2 5) chain B residue 750 type sequence S description binding site for residue 9C0 A 902 source : AC2 6) chain B residue 751 type sequence K description binding site for residue 9C0 A 902 source : AC2 7) chain B residue 752 type sequence G description binding site for residue 9C0 A 902 source : AC2 8) chain B residue 775 type sequence N description binding site for residue 9C0 A 902 source : AC2 9) chain B residue 423 type sequence E description binding site for residue ZK1 B 901 source : AC6 10) chain B residue 426 type sequence Y description binding site for residue ZK1 B 901 source : AC6 11) chain B residue 471 type sequence Y description binding site for residue ZK1 B 901 source : AC6 12) chain B residue 499 type sequence P description binding site for residue ZK1 B 901 source : AC6 13) chain B residue 500 type sequence L description binding site for residue ZK1 B 901 source : AC6 14) chain B residue 501 type sequence T description binding site for residue ZK1 B 901 source : AC6 15) chain B residue 506 type sequence R description binding site for residue ZK1 B 901 source : AC6 16) chain B residue 674 type sequence G description binding site for residue ZK1 B 901 source : AC6 17) chain B residue 675 type sequence S description binding site for residue ZK1 B 901 source : AC6 18) chain B residue 707 type sequence T description binding site for residue ZK1 B 901 source : AC6 19) chain B residue 726 type sequence E description binding site for residue ZK1 B 901 source : AC6 20) chain B residue 729 type sequence M description binding site for residue ZK1 B 901 source : AC6 21) chain B residue 753 type sequence Y description binding site for residue ZK1 B 901 source : AC6 22) chain B residue 437 type sequence E description binding site for residue ZN B 902 source : AC7 23) chain B residue 433 type sequence H description binding site for residue ZN B 903 source : AC8 24) chain B residue 475 type sequence D description binding site for residue ZN B 904 source : AC9 25) chain B residue 475 type sequence D description binding site for residue ACT B 905 source : AD1 26) chain B residue 477 type sequence D description binding site for residue ACT B 905 source : AD1 27) chain B residue 478 type sequence T description binding site for residue ACT B 905 source : AD1 28) chain B residue 474 type sequence R description binding site for residue ACT B 906 source : AD2 29) chain B residue 479 type sequence K description binding site for residue ACT B 906 source : AD2 30) chain B residue 490 type sequence Y description binding site for residue ACT B 906 source : AD2 31) chain B residue 665 type sequence E description binding site for residue ACT B 906 source : AD2 32) chain B residue 720 type sequence K description binding site for residue ACT B 906 source : AD2 33) chain B residue 433 type sequence H description binding site for residue ACT B 907 source : AD3 34) chain B residue 470 type sequence K description binding site for residue GOL B 908 source : AD4 35) chain B residue 471 type sequence Y description binding site for residue GOL B 908 source : AD4 36) chain B residue 472 type sequence G description binding site for residue GOL B 908 source : AD4 37) chain B residue 473 type sequence A description binding site for residue GOL B 908 source : AD4 38) chain B residue 482 type sequence N description binding site for residue GOL B 908 source : AD4 39) chain B residue 499 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI2 40) chain B residue 675 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI2 41) chain B residue 683 type MOD_RES sequence S description Phosphoserine; by PKC => ECO:0000250|UniProtKB:P19491 source Swiss-Prot : SWS_FT_FI3 42) chain B residue 717 type MOD_RES sequence S description Phosphoserine; by PKG => ECO:0000250|UniProtKB:P19491 source Swiss-Prot : SWS_FT_FI4 43) chain B residue 471 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559 source Swiss-Prot : SWS_FT_FI1 44) chain B residue 506 type BINDING sequence R description BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559 source Swiss-Prot : SWS_FT_FI1 45) chain B residue 726 type BINDING sequence E description BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559 source Swiss-Prot : SWS_FT_FI1

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