eF-site ID 5z8a-B
PDB Code 5z8a
Chain B

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Title Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine)
Classification TRANSFERASE
Compound C-6' aminotransferase
Source (Q70KD9_MICEC)
Sequence B:  KLLAQEPTCPRDADGRPRVFVEGSGAYLTDPDGRRWIDFD
NARGSVVLGHGDEEVAEAIARAARGRSGVGTAWSPVLDSL
LGQLQEVCGGDVVGLYRTGTAALRSVTCAVRDARDRSIVL
SSGYHGYDPMWHCDEPFTPNQHGIVEFLFDLDVLAEWLSR
PEQVAAVVISPDHMHLGERWYTEFTRLTKEADVPVIADEV
KVGLRYRAGLSTPLLDPAVWIVAKCLANGSPVAAVGGDAH
LLAALEDVSFTSYFEPTAMAAATTTLRRMATGEPQQAIRA
AGDRFIAHTRAAFANAGVPIDLAGNGNLFQFVCADDEVAD
AFHAAAAAEGLLFFEGDNQTPSAAFTDEVVEDACGRIDRV
SAALTGRFTDRELTEESWYASAWGAMDGLADRPRTREETT
AIVERLWE
Description


Functional site

1) chain B
residue 258
type
sequence F
description binding site for residues PLP A 501 and JIA A 502
source : AC1

2) chain B
residue 259
type
sequence T
description binding site for residues PLP A 501 and JIA A 502
source : AC1

3) chain B
residue 16
type
sequence T
description binding site for residues PLP B 501 and JIA B 502
source : AC2

4) chain B
residue 51
type
sequence R
description binding site for residues PLP B 501 and JIA B 502
source : AC2

5) chain B
residue 106
type
sequence T
description binding site for residues PLP B 501 and JIA B 502
source : AC2

6) chain B
residue 107
type
sequence G
description binding site for residues PLP B 501 and JIA B 502
source : AC2

7) chain B
residue 108
type
sequence T
description binding site for residues PLP B 501 and JIA B 502
source : AC2

8) chain B
residue 132
type
sequence Y
description binding site for residues PLP B 501 and JIA B 502
source : AC2

9) chain B
residue 133
type
sequence H
description binding site for residues PLP B 501 and JIA B 502
source : AC2

10) chain B
residue 134
type
sequence G
description binding site for residues PLP B 501 and JIA B 502
source : AC2

11) chain B
residue 178
type
sequence S
description binding site for residues PLP B 501 and JIA B 502
source : AC2

12) chain B
residue 206
type
sequence D
description binding site for residues PLP B 501 and JIA B 502
source : AC2

13) chain B
residue 208
type
sequence V
description binding site for residues PLP B 501 and JIA B 502
source : AC2

14) chain B
residue 209
type
sequence K
description binding site for residues PLP B 501 and JIA B 502
source : AC2

15) chain B
residue 232
type
sequence K
description binding site for residues PLP B 501 and JIA B 502
source : AC2

16) chain B
residue 342
type
sequence F
description binding site for residues PLP B 501 and JIA B 502
source : AC2

17) chain B
residue 345
type
sequence D
description binding site for residues PLP B 501 and JIA B 502
source : AC2

18) chain B
residue 346
type
sequence N
description binding site for residues PLP B 501 and JIA B 502
source : AC2

19) chain B
residue 393
type
sequence A
description binding site for residues PLP B 501 and JIA B 502
source : AC2

20) chain B
residue 395
type
sequence D
description binding site for residues PLP B 501 and JIA B 502
source : AC2

21) chain B
residue 416
type
sequence E
description binding site for residues PLP B 501 and JIA B 502
source : AC2


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