eF-site ID 5z2c-E PDB Code 5z2c Chain E click to enlarge Title Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose Classification IMMUNE SYSTEM Compound Alpha-protein kinase 1 Source (ALPK1_HUMAN) Sequence E:  NNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRA LLPSELRTLIQEAKEMKWPFVPEWQYLKDVIGAGLQQLLA SLRASILARDCAAAAAIVFLVDRFLYGLDVSGKLLQVAKG LHKLQPATPIAPQVVIRQARISVNSGKLLKAEYILSSLIS NNGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYEA AELIWASIVGYLALPQPDKKGLSTSLGILADIFVSMSKND YEKFKNNPQINLSLLKEFDHHLLSAAEACKLAAAFSAYTP LFVLTAVNIRGTCLLSYSSSNDCPPELKNLHLCEAKEAFE IGLLTKRDDEPVTGKQELHSFVKAAFGLTTVHRRLHGETG TVHAASQLCKEAMGKLYNFSTSSRSQDREALSQEVMSVIA QVKEHLQVQSFSNVDDRSYVPESFECRLDKLIL Description Functional site 1) chain E residue 61 type sequence F description binding site for residue AYU E 501 source : AC5 2) chain E residue 67 type sequence Q description binding site for residue AYU E 501 source : AC5 3) chain E residue 68 type sequence Y description binding site for residue AYU E 501 source : AC5 4) chain E residue 116 type sequence R description binding site for residue AYU E 501 source : AC5 5) chain E residue 119 type sequence Y description binding site for residue AYU E 501 source : AC5 6) chain E residue 146 type sequence Q description binding site for residue AYU E 501 source : AC5 7) chain E residue 150 type sequence R description binding site for residue AYU E 501 source : AC5 8) chain E residue 153 type sequence R description binding site for residue AYU E 501 source : AC5 9) chain E residue 195 type sequence V description binding site for residue AYU E 501 source : AC5 10) chain E residue 198 type sequence Q description binding site for residue AYU E 501 source : AC5 11) chain E residue 224 type sequence Y description binding site for residue AYU E 501 source : AC5 12) chain E residue 231 type sequence D description binding site for residue AYU E 501 source : AC5 13) chain E residue 233 type sequence K description binding site for residue AYU E 501 source : AC5 14) chain E residue 234 type sequence G description binding site for residue AYU E 501 source : AC5 15) chain E residue 236 type sequence S description binding site for residue AYU E 501 source : AC5 16) chain E residue 237 type sequence T description binding site for residue AYU E 501 source : AC5 17) chain E residue 295 type sequence F description binding site for residue AYU E 501 source : AC5 18) chain E residue 61 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 19) chain E residue 67 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 20) chain E residue 116 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 21) chain E residue 150 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 22) chain E residue 231 type BINDING sequence D description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 23) chain E residue 233 type BINDING sequence K description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 24) chain E residue 236 type BINDING sequence S description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 25) chain E residue 295 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1

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