eF-site ID 5z2c-D PDB Code 5z2c Chain D click to enlarge Title Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose Classification IMMUNE SYSTEM Compound Alpha-protein kinase 1 Source (ALPK1_HUMAN) Sequence D:  NNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRA LLPSELRTLIQEAKEMKWPFVPEKWQYKLKDVIGAGLQQL LASLRASILARDCAAAAAIVFLVDRFLYGLDVSGKLLQVA KGLHKLQPATPIAPQVVIRQARISVNSGKLLKAEYILSSL ISNNGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWY EAAELIWASIVGYLALPQPDKKGLSTSLGILADIFVSMSK NDYEKFKNNPQINLSLLKEFDHHLLSAAEACKLAAAFSAY TPLFVLTAVNIRGTCLLSYSSSNDCPPELKNLHLCEAKEA FEIGLLTKRDEPVTGKQELHSFVKAAFGLTTVHRRLHGET GTVHAASQLCKEAMGKLYNFSTSSRSQDREALSQEVMSVI AQVKEHLQVQSFSNVDDRSYVPESFECRLDKLIL Description Functional site 1) chain D residue 61 type sequence F description binding site for residue AYU D 501 source : AC4 2) chain D residue 67 type sequence Q description binding site for residue AYU D 501 source : AC4 3) chain D residue 116 type sequence R description binding site for residue AYU D 501 source : AC4 4) chain D residue 119 type sequence Y description binding site for residue AYU D 501 source : AC4 5) chain D residue 146 type sequence Q description binding site for residue AYU D 501 source : AC4 6) chain D residue 150 type sequence R description binding site for residue AYU D 501 source : AC4 7) chain D residue 153 type sequence R description binding site for residue AYU D 501 source : AC4 8) chain D residue 195 type sequence V description binding site for residue AYU D 501 source : AC4 9) chain D residue 198 type sequence Q description binding site for residue AYU D 501 source : AC4 10) chain D residue 224 type sequence Y description binding site for residue AYU D 501 source : AC4 11) chain D residue 231 type sequence D description binding site for residue AYU D 501 source : AC4 12) chain D residue 233 type sequence K description binding site for residue AYU D 501 source : AC4 13) chain D residue 234 type sequence G description binding site for residue AYU D 501 source : AC4 14) chain D residue 236 type sequence S description binding site for residue AYU D 501 source : AC4 15) chain D residue 237 type sequence T description binding site for residue AYU D 501 source : AC4 16) chain D residue 295 type sequence F description binding site for residue AYU D 501 source : AC4 17) chain D residue 61 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 18) chain D residue 67 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 19) chain D residue 116 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 20) chain D residue 150 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 21) chain D residue 231 type BINDING sequence D description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 22) chain D residue 233 type BINDING sequence K description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 23) chain D residue 236 type BINDING sequence S description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 24) chain D residue 295 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1

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