eF-site ID 5z2c-B PDB Code 5z2c Chain B click to enlarge Title Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose Classification IMMUNE SYSTEM Compound Alpha-protein kinase 1 Source (ALPK1_HUMAN) Sequence B:  NNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRA LLPSELRTLIQEAKEMKWPFVPEKWQYKQAVGPEDKTNLK DVIGAGLQQLLASLRASILARDCAAAAAIVFLVDRFLYGL DVSGKLLQVAKGLHKLQPATPIAPQVVIRQARISVNSGKL LKAEYILSSLISNNGATGTWLYRNESDKVLVQSVCIQIRG QILQKLGMWYEAAELIWASIVGYLALPQPDKKGLSTSLGI LADIFVSMSKNDYEKFKNNPQINLSLLKEFDHHLLSAAEA CKLAAAFSAYTPLFVLTAVNIRGTCLLSYSSSNDCPPELK NLHLCEAKEAFEIGLLTKRDDEPVTGKQELHSFVKAAFGL TTVHRRLHGETGTVHAASQLCKEAMGKLYNFSTSSRSQDR EALSQEVMSVIAQVKEHLQVQSFSNVDDRSYVPESFECRL DKLIL Description Functional site 1) chain B residue 61 type sequence F description binding site for residue AYU B 501 source : AC2 2) chain B residue 67 type sequence Q description binding site for residue AYU B 501 source : AC2 3) chain B residue 68 type sequence Y description binding site for residue AYU B 501 source : AC2 4) chain B residue 116 type sequence R description binding site for residue AYU B 501 source : AC2 5) chain B residue 119 type sequence Y description binding site for residue AYU B 501 source : AC2 6) chain B residue 146 type sequence Q description binding site for residue AYU B 501 source : AC2 7) chain B residue 150 type sequence R description binding site for residue AYU B 501 source : AC2 8) chain B residue 153 type sequence R description binding site for residue AYU B 501 source : AC2 9) chain B residue 195 type sequence V description binding site for residue AYU B 501 source : AC2 10) chain B residue 198 type sequence Q description binding site for residue AYU B 501 source : AC2 11) chain B residue 224 type sequence Y description binding site for residue AYU B 501 source : AC2 12) chain B residue 231 type sequence D description binding site for residue AYU B 501 source : AC2 13) chain B residue 233 type sequence K description binding site for residue AYU B 501 source : AC2 14) chain B residue 234 type sequence G description binding site for residue AYU B 501 source : AC2 15) chain B residue 236 type sequence S description binding site for residue AYU B 501 source : AC2 16) chain B residue 237 type sequence T description binding site for residue AYU B 501 source : AC2 17) chain B residue 295 type sequence F description binding site for residue AYU B 501 source : AC2 18) chain B residue 67 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 116 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 150 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 231 type BINDING sequence D description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 233 type BINDING sequence K description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 236 type BINDING sequence S description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 295 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 25) chain B residue 61 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1

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