eF-site ID 5z2c-A PDB Code 5z2c Chain A click to enlarge Title Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose Classification IMMUNE SYSTEM Compound Alpha-protein kinase 1 Source (ALPK1_HUMAN) Sequence A:  NNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRA LLPSELRTLIQEAKEMKWPFVPEKWQYKQAVGPEDKTNLK DVIGAGLQQLLASLRASILARDCAAAAAIVFLVDRFLYGL DVSGKLLQVAKGLHKLQPATPIAPQVVIRQARISVNSGKL LKAEYILSSLISNNGATGTWLYRNESDKVLVQSVCIQIRG QILQKLGMWYEAAELIWASIVGYLALPQPDKKGLSTSLGI LADIFVSMSKNDYEKFKNNPQINLSLLKEFDHHLLSAAEA CKLAAAFSAYTPLFVLTAVNIRGTCLLSYSSSNDCPPELK NLHLCEAKEAFEIGLLTKRDDEPVTGKQELHSFVKAAFGL TTVHRRLHGETGTVHAASQLCKEAMGKLYNFSTSSRSQDR EALSQEVMSVIAQVKEHLQVQSFSNVDDRSYVPESFECRL DKLIL Description Functional site 1) chain A residue 61 type sequence F description binding site for residue AYU A 501 source : AC1 2) chain A residue 67 type sequence Q description binding site for residue AYU A 501 source : AC1 3) chain A residue 68 type sequence Y description binding site for residue AYU A 501 source : AC1 4) chain A residue 116 type sequence R description binding site for residue AYU A 501 source : AC1 5) chain A residue 146 type sequence Q description binding site for residue AYU A 501 source : AC1 6) chain A residue 150 type sequence R description binding site for residue AYU A 501 source : AC1 7) chain A residue 153 type sequence R description binding site for residue AYU A 501 source : AC1 8) chain A residue 195 type sequence V description binding site for residue AYU A 501 source : AC1 9) chain A residue 198 type sequence Q description binding site for residue AYU A 501 source : AC1 10) chain A residue 224 type sequence Y description binding site for residue AYU A 501 source : AC1 11) chain A residue 231 type sequence D description binding site for residue AYU A 501 source : AC1 12) chain A residue 233 type sequence K description binding site for residue AYU A 501 source : AC1 13) chain A residue 234 type sequence G description binding site for residue AYU A 501 source : AC1 14) chain A residue 236 type sequence S description binding site for residue AYU A 501 source : AC1 15) chain A residue 237 type sequence T description binding site for residue AYU A 501 source : AC1 16) chain A residue 295 type sequence F description binding site for residue AYU A 501 source : AC1 17) chain A residue 150 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 231 type BINDING sequence D description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 19) chain A residue 233 type BINDING sequence K description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 20) chain A residue 236 type BINDING sequence S description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 295 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 61 type BINDING sequence F description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 67 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 116 type BINDING sequence R description BINDING => ECO:0000269|PubMed:30111836 source Swiss-Prot : SWS_FT_FI1

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