eF-site ID 5yzv-ABCDE PDB Code 5yzv Chain A, B, C, D, E click to enlarge Title Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA Classification PROTEIN BINDING Compound Probable serine/threonine-protein kinase PkwA Source (PKWA_THECU) Sequence A:  HELNEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWD VASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRL WDVRAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNV ATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLW DVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTVHL WDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTI RLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASEDG TIRIWP B:  NEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWDVAS GDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDV AAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLW NVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIR LWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTV HLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDR TIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASE DGTIRIWP C:  ELNEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWDV ASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLW DVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTAR LWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGT IRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDS TVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSD DRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASA SEDGTIRIWP D:  ELNEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWDV ASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLW DVAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVAT GTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDV ATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTVHLWD VASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRL WDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTI RIWP E:  NEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWDVAS GDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDV AAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLW NVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIR LWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTV HLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDR TIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASE DGTIRIWP Description Functional site 1) chain A residue 474-488 type prosite sequence LAGGSGDKLIHVWDV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAGGsgDkLIHVWDV source prosite : PS00678 2) chain A residue 516-530 type prosite sequence LASGSDDATVRLWDV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAGGsgDkLIHVWDV source prosite : PS00678 3) chain A residue 558-572 type prosite sequence VASGSRDGTARLWNV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAGGsgDkLIHVWDV source prosite : PS00678 4) chain A residue 600-614 type prosite sequence VASGSRDGTIRLWDV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAGGsgDkLIHVWDV source prosite : PS00678 5) chain A residue 683-697 type prosite sequence LASGSDDRTIRLWDV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAGGsgDkLIHVWDV source prosite : PS00678

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