eF-site ID 5yxl-C PDB Code 5yxl Chain C click to enlarge Title A ligand M binding to FXR Classification NUCLEAR PROTEIN Compound Bile acid receptor Source (E7EWM1_HUMAN) Sequence C:  TPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFL ILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAV EAMFLRSAEIFNSDLLEERIRNSGISDEYITPMFSFYKSI GELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLF TPLLCEIWDV Description Functional site 1) chain C residue 41 type sequence F description binding site for residue NIW C 301 source : AC2 2) chain C residue 44 type sequence L description binding site for residue NIW C 301 source : AC2 3) chain C residue 45 type sequence T description binding site for residue NIW C 301 source : AC2 4) chain C residue 48 type sequence A description binding site for residue NIW C 301 source : AC2 5) chain C residue 51 type sequence H description binding site for residue NIW C 301 source : AC2 6) chain C residue 85 type sequence M description binding site for residue NIW C 301 source : AC2 7) chain C residue 86 type sequence F description binding site for residue NIW C 301 source : AC2 8) chain C residue 114 type sequence I description binding site for residue NIW C 301 source : AC2 9) chain C residue 118 type sequence Y description binding site for residue NIW C 301 source : AC2 10) chain C residue 122 type sequence M description binding site for residue NIW C 301 source : AC2 11) chain C residue 200 type sequence F description binding site for residue NIW C 301 source : AC2 12) chain C residue 203 type sequence H description binding site for residue NIW C 301 source : AC2 13) chain C residue 204 type sequence H description binding site for residue NIW C 301 source : AC2 14) chain C residue 207 type sequence M description binding site for residue NIW C 301 source : AC2 15) chain C residue 226 type sequence W description binding site for residue NIW C 301 source : AC2 16) chain C residue 88 type BINDING sequence R description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 17) chain C residue 118 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 18) chain C residue 126 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 19) chain C residue 204 type BINDING sequence H description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 20) chain C residue 199 type MOD_RES sequence T description Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 source Swiss-Prot : SWS_FT_FI2 21) chain C residue 32 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 source Swiss-Prot : SWS_FT_FI3

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