eF-site ID 5yxl-ABCD PDB Code 5yxl Chain A, B, C, D click to enlarge Title A ligand M binding to FXR Classification NUCLEAR PROTEIN Compound Bile acid receptor Source (E7EWM1_HUMAN) Sequence A:  TPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFL ILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAV EAMFLRSAEIFNKSDLLEERIRNSGISDEYITPMFSFYKS IGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPL LDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEML MSWRVNDHKFTPLLCEIWDV B:  ALLRYLL C:  TPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFL ILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAV EAMFLRSAEIFNSDLLEERIRNSGISDEYITPMFSFYKSI GELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLF TPLLCEIWDV D:  ALLRYLLD Description Functional site 1) chain A residue 41 type sequence F description binding site for residue NIW A 301 source : AC1 2) chain A residue 45 type sequence T description binding site for residue NIW A 301 source : AC1 3) chain A residue 51 type sequence H description binding site for residue NIW A 301 source : AC1 4) chain A residue 85 type sequence M description binding site for residue NIW A 301 source : AC1 5) chain A residue 86 type sequence F description binding site for residue NIW A 301 source : AC1 6) chain A residue 89 type sequence S description binding site for residue NIW A 301 source : AC1 7) chain A residue 114 type sequence I description binding site for residue NIW A 301 source : AC1 8) chain A residue 118 type sequence Y description binding site for residue NIW A 301 source : AC1 9) chain A residue 122 type sequence M description binding site for residue NIW A 301 source : AC1 10) chain A residue 204 type sequence H description binding site for residue NIW A 301 source : AC1 11) chain A residue 207 type sequence M description binding site for residue NIW A 301 source : AC1 12) chain A residue 213 type sequence V description binding site for residue NIW A 301 source : AC1 13) chain A residue 226 type sequence W description binding site for residue NIW A 301 source : AC1 14) chain C residue 41 type sequence F description binding site for residue NIW C 301 source : AC2 15) chain C residue 44 type sequence L description binding site for residue NIW C 301 source : AC2 16) chain C residue 45 type sequence T description binding site for residue NIW C 301 source : AC2 17) chain C residue 48 type sequence A description binding site for residue NIW C 301 source : AC2 18) chain C residue 51 type sequence H description binding site for residue NIW C 301 source : AC2 19) chain C residue 85 type sequence M description binding site for residue NIW C 301 source : AC2 20) chain C residue 86 type sequence F description binding site for residue NIW C 301 source : AC2 21) chain C residue 114 type sequence I description binding site for residue NIW C 301 source : AC2 22) chain C residue 118 type sequence Y description binding site for residue NIW C 301 source : AC2 23) chain C residue 122 type sequence M description binding site for residue NIW C 301 source : AC2 24) chain C residue 200 type sequence F description binding site for residue NIW C 301 source : AC2 25) chain C residue 203 type sequence H description binding site for residue NIW C 301 source : AC2 26) chain C residue 204 type sequence H description binding site for residue NIW C 301 source : AC2 27) chain C residue 207 type sequence M description binding site for residue NIW C 301 source : AC2 28) chain C residue 226 type sequence W description binding site for residue NIW C 301 source : AC2 29) chain A residue 88 type BINDING sequence R description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 30) chain A residue 118 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 126 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 204 type BINDING sequence H description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 33) chain C residue 88 type BINDING sequence R description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 34) chain C residue 118 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 35) chain C residue 126 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 36) chain C residue 204 type BINDING sequence H description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 37) chain A residue 199 type MOD_RES sequence T description Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 source Swiss-Prot : SWS_FT_FI2 38) chain C residue 199 type MOD_RES sequence T description Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 source Swiss-Prot : SWS_FT_FI2 39) chain A residue 32 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 source Swiss-Prot : SWS_FT_FI3 40) chain C residue 32 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links