eF-site ID 5yxj-B PDB Code 5yxj Chain B click to enlarge Title FXR ligand binding domain Classification NUCLEAR PROTEIN Compound Bile acid receptor Source (E7EWM1_HUMAN) Sequence B:  ELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEEN FLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGS AVEAMFLRSAEIFNKHSDLLEERIRNSGISDEYITPMFSF YKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQ EPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHA EMLMSWRHKFTPLLCEIWDV Description Functional site 1) chain B residue 284 type sequence F description binding site for residue 93U B 501 source : AC2 2) chain B residue 287 type sequence L description binding site for residue 93U B 501 source : AC2 3) chain B residue 290 type sequence M description binding site for residue 93U B 501 source : AC2 4) chain B residue 294 type sequence H description binding site for residue 93U B 501 source : AC2 5) chain B residue 328 type sequence M description binding site for residue 93U B 501 source : AC2 6) chain B residue 329 type sequence F description binding site for residue 93U B 501 source : AC2 7) chain B residue 332 type sequence S description binding site for residue 93U B 501 source : AC2 8) chain B residue 357 type sequence I description binding site for residue 93U B 501 source : AC2 9) chain B residue 361 type sequence Y description binding site for residue 93U B 501 source : AC2 10) chain B residue 447 type sequence H description binding site for residue 93U B 501 source : AC2 11) chain B residue 450 type sequence M description binding site for residue 93U B 501 source : AC2 12) chain B residue 454 type sequence W description binding site for residue 93U B 501 source : AC2 13) chain B residue 469 type sequence W description binding site for residue 93U B 501 source : AC2 14) chain B residue 442 type MOD_RES sequence T description Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 source Swiss-Prot : SWS_FT_FI2 15) chain B residue 275 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 source Swiss-Prot : SWS_FT_FI3 16) chain B residue 331 type BINDING sequence R description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 17) chain B residue 361 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 369 type BINDING sequence Y description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 447 type BINDING sequence H description BINDING => ECO:0007744|PDB:6HL1 source Swiss-Prot : SWS_FT_FI1

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