eF-site ID 5yni-AB PDB Code 5yni Chain A, B click to enlarge Title Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG Classification TRANSFERASE Compound nsp16 protein Source (K4LC41_9BETC) Sequence A:  ASADWKPGHAMPSLFKVQNVNLERCELANYKQSIPMPVHM NIAKYMQLCQYLNTCTLAVPANMRVIHFGAGSDKGIAPGT SVLRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQ QVDLVISDMYDPTTKNVTGSNESKALFFTYLCNLINNNLA LGGSVAIKITEHSWSVELYELMGKFAWWTVFCTNANASSS EGFLLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTY SLFDLSKFQLKLKGTPVLQLKESQINELVISLLSQGKLLI RDNDTLSVSTDVLV B:  SSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTG TGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVC KYKGKFVQIPAQCVRDPVGFCLSNTPCNVCQYWIGYGCNC Description Functional site 1) chain A residue 43 type sequence N description binding site for residue SAM A 401 source : AC1 2) chain A residue 47 type sequence Y description binding site for residue SAM A 401 source : AC1 3) chain A residue 71 type sequence G description binding site for residue SAM A 401 source : AC1 4) chain A residue 72 type sequence A description binding site for residue SAM A 401 source : AC1 5) chain A residue 73 type sequence G description binding site for residue SAM A 401 source : AC1 6) chain A residue 80 type sequence P description binding site for residue SAM A 401 source : AC1 7) chain A residue 81 type sequence G description binding site for residue SAM A 401 source : AC1 8) chain A residue 98 type sequence N description binding site for residue SAM A 401 source : AC1 9) chain A residue 99 type sequence D description binding site for residue SAM A 401 source : AC1 10) chain A residue 100 type sequence L description binding site for residue SAM A 401 source : AC1 11) chain A residue 101 type sequence N description binding site for residue SAM A 401 source : AC1 12) chain A residue 114 type sequence D description binding site for residue SAM A 401 source : AC1 13) chain A residue 115 type sequence C description binding site for residue SAM A 401 source : AC1 14) chain A residue 130 type sequence D description binding site for residue SAM A 401 source : AC1 15) chain A residue 131 type sequence M description binding site for residue SAM A 401 source : AC1 16) chain A residue 132 type sequence Y description binding site for residue SAM A 401 source : AC1 17) chain A residue 25 type sequence C description binding site for residue GTG A 402 source : AC2 18) chain A residue 26 type sequence E description binding site for residue GTG A 402 source : AC2 19) chain A residue 27 type sequence L description binding site for residue GTG A 402 source : AC2 20) chain A residue 30 type sequence Y description binding site for residue GTG A 402 source : AC2 21) chain A residue 31 type sequence K description binding site for residue GTG A 402 source : AC2 22) chain A residue 46 type sequence K description binding site for residue GTG A 402 source : AC2 23) chain A residue 132 type sequence Y description binding site for residue GTG A 402 source : AC2 24) chain A residue 137 type sequence K description binding site for residue GTG A 402 source : AC2 25) chain A residue 170 type sequence K description binding site for residue GTG A 402 source : AC2 26) chain A residue 172 type sequence T description binding site for residue GTG A 402 source : AC2 27) chain A residue 173 type sequence E description binding site for residue GTG A 402 source : AC2 28) chain A residue 174 type sequence H description binding site for residue GTG A 402 source : AC2 29) chain A residue 201 type sequence S description binding site for residue GTG A 402 source : AC2 30) chain A residue 202 type sequence S description binding site for residue GTG A 402 source : AC2 31) chain B residue 74 type sequence C description binding site for residue ZN B 201 source : AC3 32) chain B residue 77 type sequence C description binding site for residue ZN B 201 source : AC3 33) chain B residue 83 type sequence H description binding site for residue ZN B 201 source : AC3 34) chain B residue 90 type sequence C description binding site for residue ZN B 201 source : AC3 35) chain B residue 117 type sequence C description binding site for residue ZN B 202 source : AC4 36) chain B residue 120 type sequence C description binding site for residue ZN B 202 source : AC4 37) chain B residue 128 type sequence C description binding site for residue ZN B 202 source : AC4 38) chain B residue 130 type sequence C description binding site for residue ZN B 202 source : AC4

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