eF-site ID 5yn6-AB PDB Code 5yn6 Chain A, B click to enlarge Title Crystal structure of MERS-CoV nsp10/nsp16 complex bound to SAM Classification TRANSFERASE Compound nsp16 protein Source (K4LC41_9BETC) Sequence A:  ASADWKPGHAMPSLFKVQNVNLERCELANYPMPRGVHMNI AKYMQLCQYLNTCTLAVPANMRVIHFGAGSDKGIAPGTSV LRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQQV DLVISDMYDPTSNESKALFFTYLCNLINNNLALGGSVAIK ITEHSWSVELYELMGKFAWWTVFCTNANASSSEGFLLGIN YLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKF QLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLSV STD B:  SSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTG TGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVC KYKGKFVQIPAQCVRDPVGFCLSNTPCNVCQYWIGYGCNC Description Functional site 1) chain A residue 43 type sequence N description binding site for residue SAM A 401 source : AC1 2) chain A residue 47 type sequence Y description binding site for residue SAM A 401 source : AC1 3) chain A residue 71 type sequence G description binding site for residue SAM A 401 source : AC1 4) chain A residue 73 type sequence G description binding site for residue SAM A 401 source : AC1 5) chain A residue 80 type sequence P description binding site for residue SAM A 401 source : AC1 6) chain A residue 81 type sequence G description binding site for residue SAM A 401 source : AC1 7) chain A residue 98 type sequence N description binding site for residue SAM A 401 source : AC1 8) chain A residue 99 type sequence D description binding site for residue SAM A 401 source : AC1 9) chain A residue 100 type sequence L description binding site for residue SAM A 401 source : AC1 10) chain A residue 101 type sequence N description binding site for residue SAM A 401 source : AC1 11) chain A residue 114 type sequence D description binding site for residue SAM A 401 source : AC1 12) chain A residue 115 type sequence C description binding site for residue SAM A 401 source : AC1 13) chain A residue 130 type sequence D description binding site for residue SAM A 401 source : AC1 14) chain A residue 131 type sequence M description binding site for residue SAM A 401 source : AC1 15) chain A residue 132 type sequence Y description binding site for residue SAM A 401 source : AC1 16) chain B residue 74 type sequence C description binding site for residue ZN B 201 source : AC2 17) chain B residue 77 type sequence C description binding site for residue ZN B 201 source : AC2 18) chain B residue 83 type sequence H description binding site for residue ZN B 201 source : AC2 19) chain B residue 90 type sequence C description binding site for residue ZN B 201 source : AC2 20) chain B residue 117 type sequence C description binding site for residue ZN B 202 source : AC3 21) chain B residue 120 type sequence C description binding site for residue ZN B 202 source : AC3 22) chain B residue 128 type sequence C description binding site for residue ZN B 202 source : AC3 23) chain B residue 130 type sequence C description binding site for residue ZN B 202 source : AC3

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