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Title
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Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5 |
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Classification
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VIRUS |
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Compound
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Light chain of Fab 1D5 |
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Source
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ORGANISM_SCIENTIFIC: Mus musculus; |
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Sequence
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A: |
VNEASVEHFYSRAGLVGVVEVKDSGTSLDGYTVWPIDVMG
FVQQRRKLELSTYMRFDAEFTFVSNLSNSTTPGMLLQYMY
VPPGAPKPDGRKSYQWQTATNPSVFAKLSDPPPQVSVPFM
SPATAYQWFYDGYPTNLQYGQCPNNMMGHFAIRTVSESTT
GKNVHVRVYMRIKHVRAWVPRPLRSQAYMVKNYPTYSQTI
TNTATDRASITTTD
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| B: |
NIVLSYGEWPEYCPKPTRPDVSVNRFYTLSTKSWKTESTG
WYWKFPDVLNDTGVFGQNAQFHYLYRSGFCMHVQCNASKF
HQGALLVAAIPEFVIAASSPLYPDFAHTNPGKDGQEFRDP
YVLDAGIPLSQALVFPHQWINLRTNNCATIIMPYVNALPF
DSALNHSNFGLVVIPISPLKYCNGATTEVPVTLTIAPLNS
EFSGL
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| C: |
PTELKPGTNQFLTTDDGTSPPILPGFEPTPLIHIPGEFTS
LLDLCQIETILEVNNTTGTIGVSRLLIPVRAQNNVDQLCA
SFQVDPGRNGPWQSTMVGQICRYYTQWSGSLKVTFMFTGS
FMATGKMLIAYTPPGSAQPATREAAMLGTHIVWDFGLQSS
VTLVIPWISNTGIVTIWYQTNFVVPPDTPTEANIIALGAA
QKNFTLKLCKDTDEI
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| H: |
EVQLVESGGGLVKPGGSLKLSCAASGFAFSTYDMSWVRQT
PEKRLELVAHISSGGGYIYYPDTVKGRFTISRDNAKNTLY
LQMSSLKSEDTAMYYCTRQKGLYYGFDYWGQGTTLTVSS
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| L: |
DIVMTQSHKFMSTSVGDRVSITCKASQDVNTAVAWYQQRP
GQSPKLLIYSASYRYTGVPDRFTGSGSGTDFTFTISSVQA
EDLAVYYCQQHYTTPHTFGGGTKLEIKR
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Description
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(1) |
Light chain of Fab 1D5, Heavy chain of Fab 1D5, Genome polyprotein
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