eF-site ID 5xgp-A PDB Code 5xgp Chain A click to enlarge Title structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution Classification UNKNOWN FUNCTION Compound Secreted Xwnt8 inhibitor sizzled Source (O73821_XENLA) Sequence A:  STKCVTIPTEMAMCNDVGYSEMRLPNLMGHTNMAEVVPKS AEWQNLLQTGCHPYARTFLCSLFAPVCLDTFIQPCRSMCV AVRDSCAPVLACHGHSWPESLDCDRFPAGEDMCLDTLSKS CQGCPLIEEFFSHKTVLEAFCDNNFAVKVKLAKKKSASGL YEYETEGPVEFIKQGLLLPYDTRTMIEQWLLINENCAQKL IRTRPTVYVIAGEIHHGKVKVNRIFHWQKKDSQLTLATRR WRHHKCAAA Description (1)  Secreted Xwnt8 inhibitor sizzled Functional site 1) chain A residue 26 type sequence K description binding site for residue SO4 A 301 source : AC1 2) chain A residue 28 type sequence V description binding site for residue SO4 A 301 source : AC1 3) chain A residue 47 type sequence L description binding site for residue SO4 A 301 source : AC1 4) chain A residue 55 type sequence N description binding site for residue SO4 A 301 source : AC1 5) chain A residue 56 type sequence M description binding site for residue SO4 A 301 source : AC1 6) chain A residue 35 type sequence A description binding site for residue SO4 A 302 source : AC2 7) chain A residue 36 type sequence M description binding site for residue SO4 A 302 source : AC2 8) chain A residue 67 type sequence Q description binding site for residue SO4 A 302 source : AC2 9) chain A residue 70 type sequence L description binding site for residue SO4 A 302 source : AC2 10) chain A residue 71 type sequence Q description binding site for residue SO4 A 302 source : AC2 11) chain A residue 79 type sequence R description binding site for residue SO4 A 302 source : AC2 12) chain A residue 178 type sequence N description binding site for residue CL A 303 source : AC3 13) chain A residue 258 type sequence R description binding site for residue CL A 303 source : AC3 14) chain A residue 58 type sequence E description binding site for residue CL A 304 source : AC4 15) chain A residue 161 type sequence L description binding site for residue CL A 304 source : AC4 16) chain A residue 162 type sequence I description binding site for residue CL A 304 source : AC4 17) chain A residue 234 type sequence K description binding site for residue CL A 304 source : AC4 18) chain A residue 240 type sequence P description binding site for residue CL A 305 source : AC5 19) chain A residue 115 type sequence C description binding site for residue CL A 307 source : AC6 20) chain A residue 155 type sequence S description binding site for residue CL A 307 source : AC6 21) chain A residue 263 type sequence Q description binding site for residue CL A 309 source : AC7 22) chain A residue 264 type sequence K description binding site for residue CL A 309 source : AC7 23) chain A residue 179 type sequence N description binding site for residue CL A 310 source : AC8

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