|
eF-site ID
|
5xbh-A |
PDB Code
|
5xbh |
Chain
|
A |
|
click to enlarge
|
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Title
|
Crystal structure of R145E mutant of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 |
Classification
|
TRANSFERASE |
Compound
|
Thymidylate kinase |
Source
|
Aquifex aeolicus (strain VF5) (KTHY_AQUAE) |
|
Sequence
|
A: |
MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGT
KVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDL
KRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRG
VKPDITLLLDIPVDIALRRLKEKNEFENKEFLEKVRKGFL
ELAKEEENVVVIDASGEEEEVFKEILRALSGVLR
|
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Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
7 |
type |
BINDING |
sequence |
G
|
description |
BINDING => ECO:0000255
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
A |
residue |
87-99 |
type |
prosite |
sequence |
ILDRFVLSTIAYQ
|
description |
THYMIDYLATE_KINASE Thymidylate kinase signature. ILDRFvlSTiAYQ
|
source |
prosite : PS01331
|
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